YRC Public Data Repository - Protein Structure Prediction

Protein:	AROA_ECOLI
Organism:	Escherichia coli
Length:	427 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROA_ECOLI.

Description	E-value	Query Range	Subject Range
AROA_VIBPA - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Vibrio parahaemolyticus GN=aroA PE=3 SV=1 gi\|149748099, gi... - gi\|153838532\|ref\|ZP_01991199.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Vibrio parahaemolyticu... AROA_VIBPA - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD ...	515.0	[0..1]	[424..1]
gi\|84388492, gi\|... - gi\|84388492\|ref\|ZP_00991039.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Vibrio splendidus 12B01...	514.0	[0..1]	[425..1]
gi\|85835719, gi\|... - gi\|86146456\|ref\|ZP_01064779.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Vibrio sp. MED222], gi\|...	511.0	[0..1]	[424..1]
gi\|1781351\|emb\|C... - 5-enolpyruvylshikimate-3-phosphate synthase, EC 2.5.1.19, aroA [Salmonella typhimurium] gi\|1781351, gi\|1... - pir\|\|XUEBVS 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) - Salmonella typhimurium, gi...	503.0	[0..1]	[427..1]
AROA_PHOPR - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Photobacterium profundum (strain SS9) GN=aroA PE=3 S... AROA_PHOPR - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Photobacterium profundum GN=aroA PE=3 SV=1	503.0	[0..1]	[427..1]
AROA_VIBVY - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Vibrio vulnificus (strain YJ016) GN=aroA PE=3 SV=1	502.0	[0..1]	[427..1]
AROA_SHISO - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Shigella sonnei GN=aroA PE=3 SV=1	502.0	[0..1]	[427..1]
AROA_PHOLL - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=aroA PE... AROA_PHOLL - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DS...	501.0	[0..1]	[425..1]
gi\|254287830, gi... - gi\|254287830\|ref\|YP_003053578.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Escherichia coli BL21... AROA_ECOLC - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Croo... gi\|251784450, gi... - gi\|251784450\|ref\|YP_002998754.1\| hypothetical protein B21_00919 [Escherichia coli BL21], gi\|24237672... gi\|124498229, gi... - gi\|124531967\|ref\|ZP_01702026.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Escherichia coli B], g... gi\|253972923, gi... - gi\|254161022\|ref\|YP_003044130.1\| 3-phosphoshikimate 1-carboxyvinyltransferase [Escherichia coli B st... gi\|188489450, gi... - gi\|75512064\|ref\|ZP_00734649.1\| COG0128: 5-enolpyruvylshikimate-3-phosphate synthase [Escherichia col... AROA_ECOHS - 3-phosphoshikimate 1-carboxyvinyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=aroA PE=3 SV=1 gi\|83585851, gi\|... - gi\|83585851\|ref\|ZP_00924491.1\| COG0128: 5-enolpyruvylshikimate-3-phosphate synthase [Escherichia col...	501.0	[0..1]	[427..1]
gi\|90326950, gi\|... - gi\|90412226\|ref\|ZP_01220232.1\| putative 3-phosphoshikimate 1-carboxyvinyltransferase [Photobacterium...	501.0	[0..1]	[427..1]

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Predicted Domain #1

Region A:
Residues: [1-427]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESLTLQPIA RVDGTINLPG SKSVSNRALL LAALAHGKTV LTNLLDSDDV RHMLNALTAL  60
   61 GVSYTLSADR TRCEIIGNGG PLHAEGALEL FLGNAGTAMR PLAAALCLGS NDIVLTGEPR 120
  121 MKERPIGHLV DALRLGGAKI TYLEQENYPP LRLQGGFTGG NVDVDGSVSS QFLTALLMTA 180
  181 PLAPEDTVIR IKGDLVSKPY IDITLNLMKT FGVEIENQHY QQFVVKGGQS YQSPGTYLVE 240
  241 GDASSASYFL AAAAIKGGTV KVTGIGRNSM QGDIRFADVL EKMGATICWG DDYISCTRGE 300
  301 LNAIDMDMNH IPDAAMTIAT AALFAKGTTT LRNIYNWRVK ETDRLFAMAT ELRKVGAEVE 360
  361 EGHDYIRITP PEKLNFAEIA TYNDHRMAMC FSLVALSDTP VTILDPKCTA KTFPDYFEQL 420
  421 ARISQAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	143.0
Match:	1g6sA
Description:	5-enol-pyruvyl shikimate-3-phosphate(EPSP) synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-phosphoshikimate 1-carboxyvinyltransferase activity	4.6363282422962	bayes_pls_golite062009
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	3.87711259634234	bayes_pls_golite062009
catalytic activity	2.91733519293428	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	2.15049036934665	bayes_pls_golite062009
transferase activity	1.9014276549152	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: