YRC Public Data Repository - Protein Structure Prediction

Protein:	ARGB_ECOLI
Organism:	Escherichia coli
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARGB_ECOLI.

Description	E-value	Query Range	Subject Range
ARGB_METFK - Acetylglutamate kinase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) GN=argB PE...	232.0	[0..3]	[258..27]
gi\|83595903 - gi\|83595903\|gb\|ABC25264.1\| acetylglutamate kinase [uncultured marine bacterium Ant4E12]	227.0	[0..3]	[257..56]
gi\|86356085, gi\|... - gi\|86356085\|ref\|YP_467977.1\| acetylglutamate kinase [Rhizobium etli CFN 42], gi\|86280187\|gb\|ABC89250...	227.0	[0..3]	[257..93]
ARGB_MARHV - Acetylglutamate kinase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8) ...	227.0	[0..3]	[256..20]
ARGB_NITOC - Acetylglutamate kinase OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=argB PE=3 SV=1	227.0	[0..3]	[257..28]
ARGB_PSYWF - Acetylglutamate kinase OS=Psychrobacter sp. (strain PRwf-1) GN=argB PE=3 SV=1	227.0	[0..3]	[256..28]
ARGB_SYNS9 - Acetylglutamate kinase OS=Synechococcus sp. (strain CC9902) GN=argB PE=3 SV=1	227.0	[0..3]	[258..30]
gi\|116072881, gi... - gi\|116072881\|ref\|ZP_01470146.1\| acetylglutamate kinase [Synechococcus sp. BL107], gi\|116064407\|gb\|EA...	227.0	[0..3]	[258..30]
gi\|78486238, gi\|... - gi\|78486238\|ref\|YP_392163.1\| acetylglutamate kinase [Thiomicrospira crunogena XCL-2], gi\|78364524\|gb...	227.0	[0..3]	[258..34]
ARGB_HAHCH - Acetylglutamate kinase OS=Hahella chejuensis (strain KCTC 2396) GN=argB PE=3 SV=1	226.0	[0..3]	[257..27]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNPLIIKLG GVLLDSEEAL ERLFSALVNY RESHQRPLVI VHGGGCVVDE LMKGLNLPVK  60
   61 KKNGLRVTPA DQIDIITGAL AGTANKTLLA WAKKHQIAAV GLFLGDGDSV KVTQLDEELG 120
  121 HVGLAQPGSP KLINSLLENG YLPVVSSIGV TDEGQLMNVN ADQAATALAA TLGADLILLS 180
  181 DVSGILDGKG QRIAEMTAAK AEQLIEQGII TDGMIVKVNA ALDAARTLGR PVDIASWRHA 240
  241 EQLPALFNGM PMGTRILA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	1gs5A
Description:	N-acetyl-l-glutamate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetylglutamate kinase activity	3.62493177730942	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	3.23203925555954	bayes_pls_golite062009
catalytic activity	3.20382750184555	bayes_pls_golite062009
amino acid kinase activity	2.69040298093296	bayes_pls_golite062009
transferase activity	2.54481238004476	bayes_pls_golite062009
glutamate 5-kinase activity	2.08203900247141	bayes_pls_golite062009
aspartate kinase activity	2.03700691370413	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.89315414622708	bayes_pls_golite062009
kinase activity	1.84529070582231	bayes_pls_golite062009
acetyl-CoA:L-glutamate N-acetyltransferase activity	1.28280910531626	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.72506602549224	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: