YRC Public Data Repository - Protein Structure Prediction

Protein:	AMN_ECOLI
Organism:	Escherichia coli
Length:	484 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMN_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|26248296, gi\|... - gi\|26248296\|ref\|NP_754336.1\| AMP nucleosidase [Escherichia coli CFT073], gi\|26108700\|gb\|AAN80903.1\|A... gi\|91211211, gi\|... - gi\|91211211\|ref\|YP_541197.1\| AMP nucleosidase [Escherichia coli UTI89], gi\|91072785\|gb\|ABE07666.1\| A... gi\|237704372, gi... - gi\|237704372\|ref\|ZP_04534853.1\| AMP nucleosidase [Escherichia sp. 3_2_53FAA], gi\|226900738\|gb\|EEH869...	544.0	[0..1]	[484..53]
gi\|117624172, gi... - gi\|117624172\|ref\|YP_853085.1\| AMP nucleosidase [Escherichia coli APEC O1], gi\|115513296\|gb\|ABJ01371....	544.0	[0..1]	[484..17]
gi\|188488726, gi... - gi\|188493527\|ref\|ZP_03000797.1\| AMP nucleosidase [Escherichia coli 53638], gi\|188488726\|gb\|EDU63829.... gi\|215487173, gi... - gi\|215487173\|ref\|YP_002329604.1\| AMP nucleosidase [Escherichia coli O127:H6 str. E2348/69], gi\|21526... gi\|218352326, gi... - gi\|218695594\|ref\|YP_002403261.1\| AMP nucleosidase [Escherichia coli 55989], gi\|218352326\|emb\|CAU9809... gi\|92110332 - gi\|92110332\|emb\|CAJ87600.1\| putative AMP nucleosidase [Escherichia coli] gi\|218699449, gi... - gi\|218699449\|ref\|YP_002407078.1\| AMP nucleosidase [Escherichia coli IAI39], gi\|218369435\|emb\|CAR1719... gi\|218432614, gi... - gi\|218705517\|ref\|YP_002413036.1\| AMP nucleosidase [Escherichia coli UMN026], gi\|218432614\|emb\|CAR135...	544.0	[0..1]	[484..1]
gi\|110343718, gi... - gi\|110642126\|ref\|YP_669856.1\| AMP nucleosidase [Escherichia coli 536], gi\|110343718\|gb\|ABG69955.1\| A... gi\|161486195 - gi\|161486195\|ref\|NP_754336.2\| AMP nucleosidase [Escherichia coli CFT073] gi\|162138419 - gi\|162138419\|ref\|YP_541197.2\| AMP nucleosidase [Escherichia coli UTI89] gi\|191174081, gi... - gi\|191174081\|ref\|ZP_03035596.1\| AMP nucleosidase [Escherichia coli F11], gi\|190905629\|gb\|EDV65253.1\|...	543.0	[0..1]	[484..1]
gi\|75511579 - gi\|75511579\|ref\|ZP_00734236.1\| COG0775: Nucleoside phosphorylase [Escherichia coli 53638]	543.0	[0..1]	[484..7]
gi\|75237325 - gi\|75237325\|ref\|ZP_00721371.1\| COG0775: Nucleoside phosphorylase [Escherichia coli F11] gi\|227885578, gi... - gi\|227885578\|ref\|ZP_04003383.1\| AMP nucleosidase [Escherichia coli 83972], gi\|227837151\|gb\|EEJ47617....	543.0	[0..1]	[484..7]
gi\|75255176 - gi\|75255176\|ref\|ZP_00727054.1\| COG0775: Nucleoside phosphorylase [Escherichia coli E22] gi\|75227309 - gi\|75227309\|ref\|ZP_00714096.1\| COG0775: Nucleoside phosphorylase [Escherichia coli B7A] gi\|75208364 - gi\|75208364\|ref\|ZP_00708704.1\| COG0775: Nucleoside phosphorylase [Escherichia coli B171] gi\|75186785 - gi\|75186785\|ref\|ZP_00700052.1\| COG0775: Nucleoside phosphorylase [Escherichia coli E24377A] gi\|83584582 - gi\|83584582\|ref\|ZP_00923253.1\| COG0775: Nucleoside phosphorylase [Escherichia coli 101-1]	542.0	[0..1]	[484..7]
gi\|56383568, gi\|... - gi\|56480017\|ref\|NP_707888.2\| AMP nucleosidase [Shigella flexneri 2a str. 301], gi\|56383568\|gb\|AAN435... gi\|30041691, gi\|... - gi\|30063438\|ref\|NP_837609.1\| AMP nucleosidase [Shigella flexneri 2a str. 2457T], gi\|30041691\|gb\|AAP1... gi\|110805969, gi... - gi\|110805969\|ref\|YP_689489.1\| AMP nucleosidase [Shigella flexneri 5 str. 8401], gi\|110615517\|gb\|ABF0...	542.0	[0..1]	[484..1]
gi\|75196047 - gi\|75196047\|ref\|ZP_00706117.1\| COG0775: Nucleoside phosphorylase [Escherichia coli HS]	539.0	[0..1]	[484..7]
gi\|82777475, gi\|... - gi\|82777475\|ref\|YP_403824.1\| AMP nucleosidase [Shigella dysenteriae Sd197], gi\|81241623\|gb\|ABB62333....	539.0	[0..1]	[484..1]

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Predicted Domain #1

Region A:
Residues: [1-484]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNKGSGLTP AQALDKLDAL YEQSVVALRN AIGNYITSGE LPDENARKQG LFVYPSLTVT  60
   61 WDGSTTNPPK TRAFGRFTHA GSYTTTITRP TLFRSYLNEQ LTLLYQDYGA HISVQPSQHE 120
  121 IPYPYVIDGS ELTLDRSMSA GLTRYFPTTE LAQIGDETAD GIYHPTEFSP LSHFDARRVD 180
  181 FSLARLRHYT GTPVEHFQPF VLFTNYTRYV DEFVRWGCSQ ILDPDSPYIA LSCAGGNWIT 240
  241 AETEAPEEAI SDLAWKKHQM PAWHLITADG QGITLVNIGV GPSNAKTICD HLAVLRPDVW 300
  301 LMIGHCGGLR ESQAIGDYVL AHAYLRDDHV LDAVLPPDIP IPSIAEVQRA LYDATKLVSG 360
  361 RPGEEVKQRL RTGTVVTTDD RNWELRYSAS ALRFNLSRAV AIDMESATIA AQGYRFRVPY 420
  421 GTLLCVSDKP LHGEIKLPGQ ANRFYEGAIS EHLQIGIRAI DLLRAEGDRL HSRKLRTFNE 480
  481 PPFR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	155.0
Match:	1t8rA
Description:	Crystal Structure of E. coli AMP Nucleosidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring glycosyl groups	3.98862087385485	bayes_pls_golite062009
catalytic activity	2.55312579852314	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.50597471152732	bayes_pls_golite062009
transferase activity	2.08470065362903	bayes_pls_golite062009
S-methyl-5-thioadenosine phosphorylase activity	1.78752849038946	bayes_pls_golite062009
AMP nucleosidase activity	1.51523899629982	bayes_pls_golite062009
purine-nucleoside phosphorylase activity	0.0922025632019108	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: