YRC Public Data Repository - Protein Structure Prediction

Protein:	AK3_ECOLI
Organism:	Escherichia coli
Length:	449 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AK3_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|28807726 - gi\|28807726\|dbj\|BAC60979.1\| aspartokinase III, lysine-sensitive [Vibrio parahaemolyticus RIMD 221063... gi\|28807726, gi\|... - gi\|28899490\|ref\|NP_799095.1\| aspartate kinase III [Vibrio parahaemolyticus RIMD 2210633], gi\|2880772...	383.0	[0..1]	[449..1]
gi\|36787645, gi\|... - gi\|37528208\|ref\|NP_931553.1\| aspartate kinase III [Photorhabdus luminescens subsp. laumondii TTO1], ...	381.0	[0..4]	[449..14]
gi\|75855203, gi\|... - gi\|75855203\|ref\|ZP_00762862.1\| COG0527: Aspartokinases [Vibrio sp. Ex25], gi\|116184643\|ref\|ZP_014745...	381.0	[0..1]	[449..1]
gi\|91225646, gi\|... - gi\|91225646\|ref\|ZP_01260720.1\| aspartate kinase III [Vibrio alginolyticus 12G01], gi\|91189766\|gb\|EAS...	380.0	[0..1]	[449..1]
gi\|59479046, gi\|... - gi\|59710945\|ref\|YP_203721.1\| aspartate kinase III [Vibrio fischeri ES114], gi\|59479046\|gb\|AAW84833.1...	378.0	[0..1]	[449..1]
gi\|75816807 - gi\|75816807\|ref\|ZP_00747267.1\| COG0527: Aspartokinases [Vibrio cholerae V52] gi\|229344491, gi... - gi\|229519802\|ref\|ZP_04409245.1\| aspartokinase [Vibrio cholerae RC9], gi\|229344491\|gb\|EEO09466.1\| asp... gi\|229508814, gi... - gi\|229508814\|ref\|ZP_04398306.1\| aspartokinase [Vibrio cholerae B33], gi\|229354217\|gb\|EEO19148.1\| asp... gi\|229355776, gi... - gi\|229507031\|ref\|ZP_04396537.1\| aspartokinase [Vibrio cholerae BX 330286], gi\|229355776\|gb\|EEO20696.... gi\|229220822 - gi\|229220822\|ref\|NP_230045.2\| aspartate kinase III [Vibrio cholerae O1 biovar eltor str. N16961] gi\|229368982, gi... - gi\|229606327\|ref\|YP_002876975.1\| aspartokinase [Vibrio cholerae MJ-1236], gi\|229368982\|gb\|ACQ59405.1... gi\|75828369, gi\|... - gi\|75828369\|ref\|ZP_00757804.1\| COG0527: Aspartokinases [Vibrio cholerae O395], gi\|229259768\|ref\|YP_0... gi\|75829068, gi\|... - gi\|75829068\|ref\|ZP_00758387.1\| COG0527: Aspartokinases [Vibrio cholerae MO10], gi\|116188058\|ref\|ZP_0...	375.0	[0..1]	[449..1]
gi\|116217624, gi... - gi\|75823974\|ref\|ZP_00753445.1\| COG0527: Aspartokinases [Vibrio cholerae RC385], gi\|116217624\|ref\|ZP_...	374.0	[0..1]	[449..1]
gi\|37681143, gi\|... - gi\|37681143\|ref\|NP_935752.1\| aspartate kinase III [Vibrio vulnificus YJ016], gi\|37199894\|dbj\|BAC9572...	374.0	[0..2]	[449..43]
gi\|116220376, gi... - gi\|75819731\|ref\|ZP_00749798.1\| COG0527: Aspartokinases [Vibrio cholerae V51], gi\|116220376\|ref\|ZP_01...	373.0	[0..1]	[449..1]
gi\|146316014, gi... - gi\|227116796\|ref\|YP_002818692.1\| lysine-sensitive aspartokinase III [Vibrio cholerae O395], gi\|22701... gi\|227080602, gi... - gi\|227080602\|ref\|YP_002809153.1\| lysine-sensitive aspartokinase III [Vibrio cholerae M66-2], gi\|2270... gi\|15640418, gi\|... - gi\|9654811\|gb\|AAF93564.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae O1 biovar El Tor str.... gi\|11279658 - pir\|\|F82328 aspartokinase III, lysine-sensitive VC0391 [imported] - Vibrio cholerae (strain N16961 s... gi\|121587601, gi... - gi\|121587601\|ref\|ZP_01677366.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae 2740-80], gi\|12... gi\|254850623, gi... - gi\|254850623\|ref\|ZP_05239973.1\| aspartokinase III [Vibrio cholerae MO10], gi\|254846328\|gb\|EET24742.1... gi\|153223248, gi... - gi\|153223248\|ref\|ZP_01953745.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae MAK 757], gi\|12... gi\|121630363, gi... - gi\|121727244\|ref\|ZP_01680403.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae V52], gi\|121630... gi\|153822265, gi... - gi\|153822265\|ref\|ZP_01974932.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae B33], gi\|126520... gi\|153818238, gi... - gi\|153818238\|ref\|ZP_01970905.1\| aspartokinase III, lysine-sensitive [Vibrio cholerae NCTC 8457], gi\|...	372.0	[0..6]	[449..34]

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Predicted Domain #1

Region A:
Residues: [1-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEIVVSKFG GTSVADFDAM NRSADIVLSD ANVRLVVLSA SAGITNLLVA LAEGLEPGER  60
   61 FEKLDAIRNI QFAILERLRY PNVIREEIER LLENITVLAE AAALATSPAL TDELVSHGEL 120
  121 MSTLLFVEIL RERDVQAQWF DVRKVMRTND RFGRAEPDIA ALAELAALQL LPRLNEGLVI 180
  181 TQGFIGSENK GRTTTLGRGG SDYTAALLAE ALHASRVDIW TDVPGIYTTD PRVVSAAKRI 240
  241 DEIAFAEAAE MATFGAKVLH PATLLPAVRS DIPVFVGSSK DPRAGGTLVC NKTENPPLFR 300
  301 ALALRRNQTL LTLHSLNMLH SRGFLAEVFG ILARHNISVD LITTSEVSVA LTLDTTGSTS 360
  361 TGDTLLTQSL LMELSALCRV EVEEGLALVA LIGNDLSKAC GVGKEVFGVL EPFNIRMICY 420
  421 GASSHNLCFL VPGEDAEQVV QKLHSNLFE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	2j0wA
Description:	No description for 2j0wA was found.

Predicted functions:

Term	Confidence	Notes
aspartate kinase activity	3.39058614295645	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	3.23203925555954	bayes_pls_golite062009
amino acid kinase activity	2.69040298093296	bayes_pls_golite062009
acetolactate synthase activity	2.58771218094881	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.89315414622708	bayes_pls_golite062009
kinase activity	1.84529070582231	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.7506777126472	bayes_pls_golite062009
acetylglutamate kinase activity	1.45784525332691	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
glutamate 5-kinase activity	0.537497646385449	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: