YRC Public Data Repository - Protein Structure Prediction

Protein:	AGP_ECOLI
Organism:	Escherichia coli
Length:	413 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|168767502, gi... - gi\|189363060\|gb\|EDU81479.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4486], gi\|1687675... gi\|189366549, gi... - gi\|189366549\|gb\|EDU84965.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4501], gi\|1687632... gi\|189001374, gi... - gi\|189001374\|gb\|EDU70360.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4076], gi\|1687810... gi\|13360618, gi\|... - gi\|15830412\|ref\|NP_309185.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli O157:H7 st... gi\|187770371, gi... - gi\|187770371\|gb\|EDU34215.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4196], gi\|1687736... gi\|13360618, gi\|... - gi\|15830412\|ref\|NP_309185.1\| periplasmic glucose-1-phosphatase [Escherichia coli O157:H7], gi\|133606... gi\|168754325, gi... - gi\|189358331\|gb\|EDU76750.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4401], gi\|1687543... gi\|209774010, gi... - pir\|\|B85636 periplasmic glucose-1-phosphatase [imported] - Escherichia coli (strain O157:H7, substra... gi\|168747379, gi... - gi\|188018168\|gb\|EDU56290.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4113], gi\|1687473... gi\|12514273, gi\|... - gi\|15800923\|ref\|NP_286939.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli O157:H7 ED... gi\|208822491, gi... - gi\|208822491\|ref\|ZP_03262810.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4042], gi\|208... gi\|208731493, gi... - gi\|208814845\|ref\|ZP_03256024.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|217320418, gi... - gi\|217324197\|ref\|ZP_03440281.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|209396027, gi... - gi\|209396027\|ref\|YP_002269728.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|168800635, gi... - gi\|189377111\|gb\|EDU95527.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC508], gi\|16880063... gi\|254591659, gi... - gi\|254792259\|ref\|YP_003077096.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli O157:H... gi\|168787511, gi... - gi\|189372724\|gb\|EDU91140.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC869], gi\|16878751... gi\|208728372, gi... - gi\|208808571\|ref\|ZP_03250908.1\| glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|195935259 - gi\|195935259\|ref\|ZP_03080641.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli O157:H7...	348.0	[0..1]	[413..1]
gi\|124529130, gi... - gi\|124529130\|ref\|ZP_01700240.1\| Glucose-1-phosphatase [Escherichia coli B], gi\|124500085\|gb\|EAY47563... gi\|192927759, gi... - gi\|75257445\|ref\|ZP_00728948.1\| hypothetical protein EcolE2_01002700 [Escherichia coli E22], gi\|19306... gi\|194413538, gi... - gi\|75210281\|ref\|ZP_00710443.1\| hypothetical protein EcolB_01002526 [Escherichia coli B171], gi\|19442... gi\|75195188, gi\|... - gi\|75195188\|ref\|ZP_00705258.1\| hypothetical protein EcolH_01000977 [Escherichia coli HS], gi\|1571605... gi\|218553590, gi... - gi\|218553590\|ref\|YP_002386503.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli IAI1],... gi\|169755525, gi... - gi\|170020597\|ref\|YP_001725551.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli ATCC 8...	346.0	[0..1]	[413..1]
gi\|75240609, gi\|... - gi\|75240609\|ref\|ZP_00724526.1\| hypothetical protein EcolF_01002327 [Escherichia coli F11], gi\|191172... gi\|110641185, gi... - gi\|110641185\|ref\|YP_668915.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli 536], gi\|...	346.0	[0..1]	[413..1]
gi\|218431515, gi... - gi\|218704418\|ref\|YP_002411937.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli UMN026... gi\|74311559, gi\|... - gi\|74311559\|ref\|YP_309978.1\| glucose-1-phosphatase/inositol phosphatase [Shigella sonnei Ss046], gi\|...	346.0	[0..1]	[413..1]
gi\|91210094, gi\|... - gi\|91210094\|ref\|YP_540080.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli UTI89], gi... gi\|226898228, gi... - gi\|237707018\|ref\|ZP_04537499.1\| periplasmic glucose-1-phosphatase [Escherichia sp. 3_2_53FAA], gi\|22... gi\|117623199, gi... - gi\|117623199\|ref\|YP_852112.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli APEC O1],... gi\|218364661, gi... - gi\|218557892\|ref\|YP_002390805.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli S88], ...	345.0	[0..1]	[413..1]
gi\|191166951, gi... - gi\|75229923\|ref\|ZP_00716440.1\| hypothetical protein EcolB7_01001854 [Escherichia coli B7A], gi\|19116...	345.0	[0..1]	[413..1]
gi\|157158962, gi... - gi\|75190066\|ref\|ZP_00703333.1\| hypothetical protein EcolE_01003360 [Escherichia coli E24377A], gi\|15...	345.0	[0..1]	[413..1]
gi\|192955904, gi... - gi\|75234365\|ref\|ZP_00718735.1\| hypothetical protein EcolE1_01003738 [Escherichia coli E110019], gi\|1...	345.0	[0..1]	[413..1]
gi\|56479794, gi\|... - gi\|56479794\|ref\|NP_706925.2\| glucose-1-phosphatase/inositol phosphatase [Shigella flexneri 2a str. 3... gi\|110805018, gi... - gi\|110805018\|ref\|YP_688538.1\| glucose-1-phosphatase/inositol phosphatase [Shigella flexneri 5 str. 8... gi\|30040785, gi\|... - gi\|30062539\|ref\|NP_836710.1\| glucose-1-phosphatase/inositol phosphatase [Shigella flexneri 2a str. 2...	344.0	[0..1]	[413..1]
gi\|242376816, gi... - gi\|251784543\|ref\|YP_002998847.1\| hypothetical protein B21_01012 [Escherichia coli BL21], gi\|24237681... gi\|253973016, gi... - gi\|254161115\|ref\|YP_003044223.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli B str.... gi\|253325012, gi... - gi\|254287923\|ref\|YP_003053671.1\| glucose-1-phosphatase/inositol phosphatase [Escherichia coli BL21(D... gi\|194423030, gi... - gi\|83586454\|ref\|ZP_00925088.1\| hypothetical protein Ecol1_01002348 [Escherichia coli 101-1], gi\|1944...	344.0	[0..1]	[413..1]

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Predicted Domain #1

Region A:
Residues: [1-413]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKTLIAAAV AGIVLLASNA QAQTVPEGYQ LQQVLMMSRH NLRAPLANNG SVLEQSTPNK  60
   61 WPEWDVPGGQ LTTKGGVLEV YMGHYMREWL AEQGMVKSGE CPPPYTVYAY ANSLQRTVAT 120
  121 AQFFITGAFP GCDIPVHHQE KMGTMDPTFN PVITDDSAAF SEQAVAAMEK ELSKLQLTDS 180
  181 YQLLEKIVNY KDSPACKEKQ QCSLVDGKNT FSAKYQQEPG VSGPLKVGNS LVDAFTLQYY 240
  241 EGFPMDQVAW GEIKSDQQWK VLSKLKNGYQ DSLFTSPEVA RNVAKPLVSY IDKALVTDRT 300
  301 SAPKITVLVG HDSNIASLLT ALDFKPYQLH DQNERTPIGG KIVFQRWHDS KANRDLMKIE 360
  361 YVYQSAEQLR NADALTLQAP AQRVTLELSG CPIDADGFCP MDKFDSVLNE AVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.221849
Match:	1nt4A
Description:	Crystal structure of Escherichia coli periplasmic glucose-1-phosphatase H18A mutant complexed with glucose-1-phosphate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.84708627579827	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: