YRC Public Data Repository - Protein Structure Prediction

Protein:	ACEK_ECOLI
Organism:	Escherichia coli
Length:	578 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACEK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|193062982, gi... - gi\|75258935\|ref\|ZP_00730303.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col... ACEK_ECOSE - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli (strain SE11) GN=aceK PE=3 SV=1 gi\|75229419, gi\|... - gi\|75229419\|ref\|ZP_00715971.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col... ACEK_ECO8A - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli O8 (strain IAI1) GN=aceK PE=3 SV=1 ACEK_ECOHS - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli O9:H4 (strain HS) GN=aceK PE=3 SV=1 ACEK_ECO24 - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=... ACEK_ECO55 - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli (strain 55989 / EAEC) GN=aceK PE=3 S...	979.0	[0..1]	[578..1]
gi\|75211898, gi\|... - gi\|75211898\|ref\|ZP_00711953.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col...	978.0	[0..1]	[578..1]
gi\|208739433, gi... - gi\|208819310\|ref\|ZP_03259630.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H... ACEK_ECO5E - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ac... gi\|217320941, gi... - gi\|217324720\|ref\|ZP_03440804.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H... ACEK_ECO57 - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli O157:H7 GN=aceK PE=1 SV=1 gi\|168798353, gi... - gi\|189379139\|gb\|EDU97555.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|195935774 - gi\|195935774\|ref\|ZP_03081156.1\| bifunctional isocitrate dehydrogenase kinase/phosphatase protein [Es... gi\|25288059, gi\|... - pir\|\|D86093 isocitrate dehydrogenase kinase/phosphatase [imported] - Escherichia coli (strain O157:H... gi\|208727351, gi... - gi\|208807550\|ref\|ZP_03249887.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H... gi\|208813111, gi... - gi\|208813111\|ref\|ZP_03254440.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H... gi\|189364194, gi... - gi\|189364194\|gb\|EDU82613.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|254595409, gi... - gi\|254796009\|ref\|YP_003080846.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:... gi\|15804602, gi\|... - gi\|15804602\|ref\|NP_290643.1\| bifunctional isocitrate dehydrogenase kinase/phosphatase protein [Esche... gi\|187769854, gi... - gi\|187769854\|gb\|EDU33698.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|189001783, gi... - gi\|189001783\|gb\|EDU70769.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|15834188, gi\|... - gi\|15834188\|ref\|NP_312961.1\| bifunctional isocitrate dehydrogenase kinase/phosphatase protein [Esche... gi\|189374982, gi... - gi\|189374982\|gb\|EDU93398.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|168750865, gi... - gi\|188015011\|gb\|EDU53133.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|189357464, gi... - gi\|189357464\|gb\|EDU75883.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st... gi\|168760850, gi... - gi\|189368548\|gb\|EDU86964.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 st...	978.0	[0..1]	[578..1]
ACEK_SHIDS - Isocitrate dehydrogenase kinase/phosphatase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=ace...	977.0	[0..1]	[578..1]
gi\|193067923, gi... - gi\|75238553\|ref\|ZP_00722542.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col...	977.0	[0..1]	[578..1]
ACEK_ECOLC - Isocitrate dehydrogenase kinase/phosphatase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crook... gi\|124531696, gi... - gi\|124531696\|ref\|ZP_01701864.1\| Isocitrate dehydrogenase kinasephosphatase [Escherichia coli B], gi\|... gi\|253326403, gi... - gi\|254290703\|ref\|YP_003056451.1\| bifunctional isocitrate dehydrogenase kinase/phosphatase protein [E... gi\|251787274, gi... - gi\|251787274\|ref\|YP_003001578.1\| hypothetical protein B21_03848 [Escherichia coli BL21], gi\|24237954... gi\|188490290, gi... - gi\|75514778\|ref\|ZP_00737007.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col... gi\|253975854, gi... - gi\|254163953\|ref\|YP_003047061.1\| bifunctional isocitrate dehydrogenase kinase/phosphatase protein [E... gi\|194437269, gi... - gi\|83587111\|ref\|ZP_00925740.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Escherichia col...	977.0	[0..1]	[578..1]
ACEK_SHIB3 - Isocitrate dehydrogenase kinase/phosphatase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS5...	975.0	[0..1]	[578..1]
gi\|89104259 - gi\|89104259\|ref\|ZP_01176807.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Yersinia pestis... gi\|77630656, gi\|... - gi\|77630656\|ref\|ZP_00793242.1\| COG4579: Isocitrate dehydrogenase kinase/phosphatase [Yersinia pseudo...	973.0	[0..1]	[572..38]
gi\|146444 - gi\|146444\|gb\|AAA24010.1\| isocitrate dehydrogenase kinase/phosphatase [Escherichia coli]	973.0	[0..1]	[578..1]
ACEK_YERPS - Isocitrate dehydrogenase kinase/phosphatase OS=Yersinia pseudotuberculosis GN=aceK PE=3 SV=1 ACEK_YERPS - Isocitrate dehydrogenase kinase/phosphatase OS=Yersinia pseudotuberculosis serotype I (strain IP3295...	970.0	[0..1]	[572..1]

Back

Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRGLELLIA QTILQGFDAQ YGRFLEVTSG AQQRFEQADW HAVQQAMKNR IHLYDHHVGL  60
   61 VVEQLRCITN GQSTDAAFLL RVKEHYTRLL PDYPRFEIAE SFFNSVYCRL FDHRSLTPER 120
  121 LFIFSSQPER RFRTIPRPLA KDFHPDH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [148-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GWESLLMRVI SDLPLRLRWQ NKSRDIHYII RHLTETLGTD NLAESHLQVA NELFYRNKAA  60
   61 WLVGKLITPS GTLPFLLPIH QTDDGELFID TCLTT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [243-420]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAEASIVFGF ARSYFMVYAP LPAALVEWLR EILPGKTTAE LYMAIGCQKH AKTESYREYL  60
   61 VYLQGCNEQF IEAPGIRGMV MLVFTLPGFD RVFKVIKDRF APQKEMSAAH VRACYQLVKE 120
  121 HDRVGRMADT QEFENFVLEK RHISPALMEL LLQEAAEKIT DLGEQIVIRH LYIERRMV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [421-578]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLNIWLEQVE GQQLRDAIEE YGNAIRQLAA ANIFPGDMLF KNFGVTRHGR VVFYDYDEIC  60
   61 YMTEVNFRDI PPPRYPEDEL ASEPWYSVSP GDVFPEEFRH WLCADPRIGP LFEEMHADLF 120
  121 RADYWRALQN RIREGHVEDV YAYRRRQRFS VRYGEMLF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits