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View Structure Prediction Details

Protein: twk-36
Organism: Caenorhabditis elegans
Length: 562 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twk-36.

Description E-value Query
Range
Subject
Range
gi|50760596 - gi|50760596|ref|XP_418075.1| PREDICTED: potassium voltage-gated channel, subfamily H (eag-related), ...
234.0 [0..51] [549..396]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTSEKDGL KSILSQKYTV ERKDTVQHVL EGPGLSRNQS NASVLTLPGS RNTSSNHLPA  60
   61 QRSTSVDEVA RHRVTYEMDA GKSEKSENQN PIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYYQKNHYTV TGNQETYQKL PRNISANRFQ VDKASISQKS APRASEPMEM PMLPQERQFD  60
   61 KSFYWF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [160-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMHRKKFGLR YIALLVLALI YTLLGATVFY LIEGSNEKSR LHVREQNLDK LLDELATVLS  60
   61 EAVNDPEQSS EHQRMKEFIK ESYISLQKHE EQYKWSTYYR LEHPDNLKWT FSSAFFFSMN 120
  121 VYTTTGYGSI SAQTFSGQLF TMIYAFCFVP VTLVILRDLG QMFLVNFTKL YAHGLTAVRR 180
  181 IRGKREVDED EIIQLPIKFC MTILIAYLLL CTTFVYLYDA VMGPEWDDGL PYFTAFYFSF 240
  241 ISLTTIGLGD VMPNNVPYAP PVSMIFFIGM AVTKVVNRAT FIAVENGVFG LMTLAETKIS 300
  301 MLLTERKPGV KTVRSTSSGS SAESVDSKEP RGFDGDSDSG SDDGVINRRR NEMMNTFTVR 360
  361 SIATFMRSNH DVYGGGFGRV QLRRGDLMSS NALHTVPWVR PLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle