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View Structure Prediction Details

Protein: acr-23
Organism: Caenorhabditis elegans
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-23.

Description E-value Query
Range
Subject
Range
gi|221222659, gi... - gi|91077638|ref|XP_974090.1| PREDICTED: similar to CG5610-PA [Tribolium castaneum], gi|221222659|gb|...
399.0 [0..11] [544..13]

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Predicted Domain #1
Region A:
Residues: [1-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRIYTFLIF ISQLALGLSN NPDIPIQYEL ANNIMENYQK GLIPKVRKGS PINVTLSLQL  60
   61 YQIIQVNEPQ QYLLLNAWAV ERWVDQMLGW DPSEFDNETE IMARHDDIWL PDTTLYNSLE 120
  121 MDDSASKKLT HVKLTTLGKN QGAMVELLYP TIYKISCLLN LKYFPFDTQT CRMTFGSWSF 180
  181 DNSLIDYFPR TFTNGPIGLA NFLENDAWSV LGTKVNREEK KYTCCPVNYT LLHYDVVIQR 240
  241 KPLYYVLNLI APTAVITFIS IIGFFTSVNP FTNFCNVSSS VHDLRQEKIT LGITTLLSMS 300
  301 IMIFMVSDKM PSTSTCVPLI ALFYTLMITI ISVGTLAASS VIFVQKLGSI GNPPASKTMK 360
  361 WTHRIAPFVL IQMP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.69897
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [375-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVMKQAYAKR AKEEKHRKRM SRKNSMWTKV YHLARDHSKL METVPDGAVK FNQISDFKNN  60
   61 DIGNMESPRM AESQTSETFA APMDTSFTES LHIPELNRVA SSNSIQSVLK PTEIQLTPYC 120
  121 TRNIVELEWD WVAAVLERVF LIFFTICFLF SAIGINLYGW YIWYTENHFL F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.30103
Match: 1oedE
Description: Acetylcholine receptor protein, gamma chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle