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View Structure Prediction Details

Protein: gi|7270183, gi|2...
Organism: Arabidopsis thaliana
Length: 765 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7270183, gi|2....

Description E-value Query
Range
Subject
Range
gi|109115580 - gi|109115580|ref|XP_001113201.1| PREDICTED: similar to breast cancer 1, early onset isoform BRCA1-de...
269.0 [0..170] [761..119]
gi|119581326, gi... - gi|6552321|ref|NP_009236.1| breast cancer 1, early onset isoform BRCA1-delta9-10-11b [Homo sapiens],...
268.0 [0..170] [761..119]
gi|29647951 - gi|29647951|gb|AAO92398.1|AF479648_1 breast and ovarian cancer susceptibility protein variant BRCA1-...
247.0 [0..162] [757..111]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEDFASDL QSPSASSDHR FEVNRILGCG EIEDTEAIDE ALVLNSSLLE TPFQVLYDDT  60
   61 ELVDNGNCGD EESLNQECYG LDQVVVDDSD DEDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.689 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.524 a.46.1 Methionine synthase domain
View Download 0.523 a.46.1 Methionine synthase domain
View Download 0.519 a.118.1 ARM repeat
View Download 0.481 a.4.1 Homeodomain-like
View Download 0.456 a.46.1 Methionine synthase domain
View Download 0.456 a.77.1 DEATH domain
View Download 0.405 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.404 a.4.5 "Winged helix" DNA-binding domain
View Download 0.270 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.225 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.225 a.4.1 Homeodomain-like
View Download 0.205 a.200.1 Description not found.

Predicted Domain #2
Region A:
Residues: [95-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVAAGEPMCL PELSPKAGDI LLESDGSNDH ECQTGKQESN CDTVTGFQGS LRITASSHGP  60
   61 GLDFLDSQEP GESTQADALG FVDHFLMDKD LNLSPVDLPV NSCRRKSSPV SGAKGCQSLA 120
  121 KRIMSRSPTR KMSVFDWSSD QCDVSDPKTS PVTRAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [251-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITCSKIREDQ VAGDDFGVKK RSRDPCDIRK VSSHPTQRVM KNSSAKHLKM EQASGLSEGI  60
   61 MFISQKDAQL EDKAPKEPLE PEEDFIDIGI NTQIAAEAMS ALVYAPCTTE EACESDPIPG 120
  121 SVSEMRDQVS NLSRRNNDTI EGEPERDKLN GLFSAAPHRE RNSKKKRKFT NEERTRANVS 180
  181 VKTCLLNLCE WRHPRAKRSR LMQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [454-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHHVPPRRSW GASLVKDRSE TNTLSSSLRG SLSGTRQASS CQSGVIDLNV AYHASPRKIY  60
   61 DGSHESPCNK DFPRLFLQKE LTTSLGGPGK IGDFVWKDLR KR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.796 a.74.1 Cyclin-like
View Download 0.796 a.74.1 Cyclin-like
View Download 0.580 a.74.1 Cyclin-like
View Download 0.580 a.74.1 Cyclin-like
View Download 0.556 a.74.1 Cyclin-like
View Download 0.556 a.74.1 Cyclin-like
View Download 0.483 a.74.1 Cyclin-like
View Download 0.483 a.74.1 Cyclin-like
View Download 0.447 a.74.1 Cyclin-like
View Download 0.424 a.74.1 Cyclin-like
View Download 0.376 a.59.1 PAH2 domain
View Download 0.284 a.74.1 Cyclin-like
View Download 0.218 a.4.12 TrpR-like

Predicted Domain #5
Region A:
Residues: [556-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNLAHVRVLF SQNLDDETVK QQKKIMVRLG ISPASSSADS THFIADRFAR TRNMLEAIAL  60
   61 GKFVVTPIWL ESCAQTRCLI DEKSYILRDI KKEKDGFCLL TSLARAKQHP LLKGFKVCIT 120
  121 PSIKPSRGMI TDLVKMTQGQ VVEASEIIAA EDRNFPEDVL ILSCKEDRDF CLPFVNQGTV 180
  181 SSQFQRKGTK EIHKFTAACL LLSTTDWYKQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 2azmA
Description: Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle