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View Structure Prediction Details

Protein: UPL4_ARATH
Organism: Arabidopsis thaliana
Length: 1502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for UPL4_ARATH.

Predicted Domain #1
Region A:
Residues: [1-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENRGQKRME VVEELPADKR ACNSQDFRPS TSGSSVQAQA NDTNPGHENV DADMDTSSSA  60
   61 SPSSRSDEEE QEEQDKEDSD YGSCDSDEED PRQRVLQDYQ RQRSSGDHGK LKSLLLNLTG 120
  121 ETDPSGQLSR LTELCEVLSF STEESLSSVM ANMLSPVLVK LAKHENNADI MLLAIRAITY 180
  181 LCDVYPPSVE FLVRHDTIPA LCQRLLTIEY LDVAEQCLQA LEKISRDEPV ACLNAGAIMA 240
  241 VLSFIDFFST SIQRVAISTV VNICKQLSSE SPSPFMDAVP ILCTLLQYED RQLVENVAIC 300
  301 LTKIADQASE SPAMLDQLCR HGLINESTHL LNLNSRTTLS QPVYNGVIGM LRKLSSGSAL 360
  361 AFRTLYELNI GYSLKEIMST YDISHSVSST HPINACSNQV HEVLKLVIEL LPASPVEDNQ 420
  421 LASEKESFLV NQPDLLQQFG RDMLPVMIQV LNSGANVYVS YGCLSAIHKL TCLSKSGDIV 480
  481 ELLKNTNMSS VLAGILSRKD HHVIVVALQV AEVLLEKYRD TFLNSFIKEG VFFAIEALLS 540
  541 SDRGQQNQGS ADLSQKPVTK EIVKCLCQSF ERSLSSSSQT CK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.221849
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [583-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEKDSVYVLA TRIKEGFFGP EVFNSEKGLT DVLQNLKNLS VALSELMTVP ID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1w63B
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [635-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHVLHDEKFF SIWNQIMERL NGRESVSTFE FIESGVVKSL ASYLSNGLYQ RKLSKGGPEC  60
   61 DSLPFIGKRF EVFTRLLWSD GEATSSLLIQ KLQNSLSSLE NFPIVLSQFL KQKNSFAAIP 120
  121 NGRCTSYPCL KVRFLKAEGE TSLRDYSQDF VTVDPLCYLD AVDQYLWPKV NIEPIDSVEA 180
  181 KDQAIECQSS QLQSTSISCQ AE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [837-914]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSPMEIDSE SSDASQLQGS QVEDQTQLPG QQNASSSETS SEKEDAVPRL LFRLEGLELD  60
   61 RSLTVYQAIL LHKLKSES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [915-1023]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EATNDSKLSG PHNITYERSA QLGDSRENLF PPGSMEDDEY RPFLSYLFTH RLALRLKGSS  60
   61 HPPYDILFLL KSLEGMNRFL FHLISLERIN AFGEGRLENL DDLRVQVRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1024-1502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPHSEFVSSK LTEKLEQQLR DSFAVSTCGL PPWFNDLMDS CPCLFSFEAK SKYFRLAAFG  60
   61 SQKIRHHPQH LSSSNVHGEA RPVTGSLPRK KFLACRENIL ESAAKMMELY GNQKVVIEVE 120
  121 YSEEVGTGLG PTLEFYTLVS RAFQNPDLGM WRNDCSFIVG KPVEHSGVLA SSSGLFPRPW 180
  181 SGTSTTSDVL QKFVLLGTVV AKALQDGRVL DLPLSKAFYK LILGQELSSF DIHFVDPELC 240
  241 KTLVELQALV RRKKLFAEAH GDSGAAKCDL SFHGTKIEDL CLEFALPGYT DYDLAPYSAN 300
  301 DMVNLDNLEE YIKGIVNATV CNGIQKQVEA FRSGFNQVFS IEHLRIFNEE ELETMLCGEC 360
  361 DLFSMNEVLD HIKFDHGYTS SSPPVEYLLQ ILHEFDREQQ RAFLQFVTGS PRLPHGGLAS 420
  421 LSPKLTIVRK HGSDSSDTDL PSVMTCANYL KLPPYSSKEK MKEKLIYAIT EGQGSFHLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 110.0
Match: 1zvdA
Description: Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle