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View Structure Prediction Details

Protein: SMC5_ARATH
Organism: Arabidopsis thaliana
Length: 1053 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for SMC5_ARATH.

Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERRAKRPK ISRGEDDFLP GNIIEIELHN FMTFNHLVCK PGSRLNLVIG PNGSGKSSLV  60
   61 CAIALCLGGE PQLLGRATSV GAYVKRGEDS GYVKISLRGN TREENLTIFR KIDTRNKSEW 120
  121 MFNGSTVSKK DIVEIIQKFN IQVNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1w1wA
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [146-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTQFLPQDRV CEFAKLTPVQ LLEETEKAVG DPQLPVHHRA LVEKSRDLKQ LERAVAKNGE  60
   61 TLNQLKALVD EQEKDVERVR QRELFLTKVD SMKKKLPWLK YDMKKAEYMD AKKRMKEAEK 120
  121 KLDEAAKNLN SMKEPIEKQK KEKAETDSKC KKVKNLMDAN GRNRCHLLEK EDEADARVVA 180
  181 TYKELEELKK QEEHRQERIL KATEDLVAAE RELQNLPVYE RPVAKLEELS SQVTELHHSI 240
  241 NGKKNQKEDN EKLLSQKRYT LRQCVDKLKD MENANNKLLK ALANSGADRI FDAYQWVQQN 300
  301 RHEFKREVYG PVLVEVNVPN RENACFLEGH VSFYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [481-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKSFITQDPE DRDLLVKNLK RFDVPVLNYV GNSGNQKAPF HISDQMRSLG IHARLDQIFD  60
   61 APDAVKEVLN SQFGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [556-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDSYIGSKIT DQRAEEVYKL GIKDFWTPDN HYRWSSSRYG GHSSASVDSV YQSRLLLCGV  60
   61 DVGELEKLRS RKEELEDSIL FMEETHKSLQ TEQRRLEEEA AKLHKEREEI VNVSYLEKKK 120
  121 RRELESRYQQ RKTKLESLEQ EEDMDASVAK LIDQASRANA DRYTYAINLK KLLVEAVAHK 180
  181 WSYAEKHMAS IELERKIRES EINIKQYEKT AQQLSLAVEY CKKEVEGKQQ RLATAKRDAE 240
  241 SVATITPELK KEFMEMPTTV EELEAAIQDN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1dg3A
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [826-883]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSQANSILFI NENILQEYEH RQSQIYTIST KLETDKRDLS ICMKEIDSLK EKWLPTLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [884-961]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLVGQINETF SHNFQEMAVA GEVSLDERDT DFDQYGIHIK VKFRESGQLQ VLSSHHQSGG  60
   61 ERSVSTILYL VSLQDLTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [962-1053]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPFRVVDEIN QGMDPINERK MFQQLVRAAS QPNTPQCFLL TPKLLPELEY SEACSILNIM  60
   61 NGPYIAEPSK VWSLGDSWGS LNRRRTEASQ CS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1xewY
Description: Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle