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View Structure Prediction Details

Protein: PUS6_ARATH
Organism: Arabidopsis thaliana
Length: 472 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUS6_ARATH.

Description E-value Query
Range
Subject
Range
gi|89516007, gi|... - gi|89891672|ref|ZP_01203175.1| ribosomal large subunit pseudouridine synthase D [Flavobacteria bacte...
307.0 [0..138] [461..30]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPALTGGY RNLTAPVSLL RTLASTRVTT PLFRSNKHSP RFISSPKRFT CLSLLKTDSQ  60
   61 NQTTLSSSSN SGYHEYNRLM PCPAYN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPRIEHMVV LEDDVLVSEF ISKQLDLPPL YVADLIRFGA VHYALVCPKP PPTATPEEII  60
   61 LFEEVTSPSV LKKRSSIKGK TVREAQKTFR VTHTNQYAEA GTYLRVHVHP KRSPRCYEID 120
  121 WKSRIVAVTD SYVILDKPAG TTVGGTTDNI EESCATFASR ALDLPEPLKT THQIDNCTEG 180
  181 CVVFARTKEY CSVFHTKIRN KEVKKLYRAL AAAPLPIGII SHYMRPKNMA PRLVAEDSIQ 240
  241 GWHLCQLEVL ECKKIPWPDA ATEKKHDIED CGWTSKEFAY ECTINLLTGK THQIRAQLAA 300
  301 CGAPLVGDSM YMPAAIAEMG NPDTNPYGKA KKHYTMEENQ KETAVAEWID RHGKEPRVGI 360
  361 GLQACQISWD DDDGEHFYEA GTPWWR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.30103
Match: 1qyuA
Description: Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.49175104308599 bayes_pls_golite062009
isomerase activity 0.87098451300632 bayes_pls_golite062009
intramolecular transferase activity 0.86450504855635 bayes_pls_golite062009
pseudouridine synthase activity 0.86297783328106 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle