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View Structure Prediction Details

Protein: AED3_ARATH
Organism: Arabidopsis thaliana
Length: 449 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AED3_ARATH.

Description E-value Query
Range
Subject
Range
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
311.0 [0..13] [447..3]

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Predicted Domain #1
Region A:
Residues: [1-449]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSSLHFFF FLTLLLPFTF TTATRDTCAT AAPDGSDDLS IIPINAKCSP FAPTHVSASV  60
   61 IDTVLHMASS DSHRLTYLSS LVAGKPKPTS VPVASGNQLH IGNYVVRAKL GTPPQLMFMV 120
  121 LDTSNDAVWL PCSGCSGCSN ASTSFNTNSS STYSTVSCST AQCTQARGLT CPSSSPQPSV 180
  181 CSFNQSYGGD SSFSASLVQD TLTLAPDVIP NFSFGCINSA SGNSLPPQGL MGLGRGPMSL 240
  241 VSQTTSLYSG VFSYCLPSFR SFYFSGSLKL GLLGQPKSIR YTPLLRNPRR PSLYYVNLTG 300
  301 VSVGSVQVPV DPVYLTFDAN SGAGTIIDSG TVITRFAQPV YEAIRDEFRK QVNVSSFSTL 360
  361 GAFDTCFSAD NENVAPKITL HMTSLDLKLP MENTLIHSSA GTLTCLSMAG IRQNANAVLN 420
  421 VIANLQQQNL RILFDVPNSR IGIAPEPCN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.154902
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.01508543827677 bayes_pls_golite062009
hydrolase activity 0.77554493777157 bayes_pls_golite062009
peptidase activity 0.68518523369811 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.43925265235199 bayes_pls_golite062009
endopeptidase activity 0.43264884039584 bayes_pls_golite062009
aspartic-type endopeptidase activity 0.30585066730542 bayes_pls_golite062009
aspartic-type peptidase activity 0.30585066730542 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle