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View Structure Prediction Details

Protein: FH1_ARATH
Organism: Arabidopsis thaliana
Length: 1051 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FH1_ARATH.

Description E-value Query
Range
Subject
Range
gi|73989079 - gi|73989079|ref|XP_857344.1| PREDICTED: similar to diaphanous homolog 3 isoform 4 [Canis familiaris]
426.0 [0..575] [1047..492]
gi|110741802 - gi|110741802|dbj|BAE98844.1| formin-like protein AHF1 [Arabidopsis thaliana]
419.0 [0..21] [1051..17]
gi|109502797 - gi|109502797|ref|XP_001074393.1| PREDICTED: similar to Protein diaphanous homolog 3 (Diaphanous-rela...
416.0 [0..575] [1047..603]
gi|111598672 - gi|111598672|gb|AAH85191.1| Diaphanous homolog 3 (Drosophila) [Mus musculus]
414.0 [0..575] [1047..602]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFFLFFFYL LLSSSSDLVF ADRRVLHEPF FPIDSPPPSP PSPPPLPKLP FSSTTPPSSS  60
   61 DPNASPFFPL YPSSPPPPSP ASFASFPANI SSLIVPHATK SPPNSKKLLI VAISAVSSAA 120
  121 LVALLIALLY WRRSKRNQDL NFSDDSKTYT TDSSRRVYPP PPATAPPTRR NAEARSKQRT 180
  181 TTSSTNNNSS EFLYLGTMVN Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [202-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGIDEQSLSN NGSSSRKLES PDLQPLPPLM KRSFRLNPDV GSIGEEDEED EFYSPRGSQS  60
   61 GREPLNRVGL PGQNPRSVNN DTISCSSSSS GSPGRSTFIS ISPSMSPKRS EPKPPVISTP 120
  121 EPAELTDYRF VRSPSLSLAS LSSGLKNSDE VGLNQIFRSP TVTSLTTSPE NNKKENSPLS 180
  181 STSTSPERRP NDTPEAYLRS PSHSSASTSP YRCFQKSPEV LPAFMSNLRQ G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [433-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQSQLLSSPS NSHGGQGFLK QLDALRSRSP SSSSSSVCSS PEKASHKSPV TSPKLSSRNS  60
   61 QSLSSSPDRD FSHSLDVSPR ISNISPQILQ SRVPPPPPPP PPLPLWGRRS QVTTKADTIS 120
  121 RPPSLTPPSH P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [564-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVIPSENLPV TSSPMETPET VCASEAAEET PKPKLKALHW DKVRASSDRE MVWDHLRSSS  60
   61 FKLDEEMIET LFVAKSLNNK PNQSQTTPRC VLPSPNQENR VL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [666-1051]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPKKAQNIAI LLRALNVTIE EVCEALLEGN ADTLGTELLE SLLKMAPTKE EERKLKAYND  60
   61 DSPVKLGHAE KFLKAMLDIP FAFKRVDAML YVANFESEVE YLKKSFETLE AACEELRNSR 120
  121 MFLKLLEAVL KTGNRMNVGT NRGDAHAFKL DTLLKLVDVK GADGKTTLLH FVVQEIIRAE 180
  181 GTRLSGNNTQ TDDIKCRKLG LQVVSSLCSE LSNVKKAAAM DSEVLSSYVS KLSQGIAKIN 240
  241 EAIQVQSTIT EESNSQRFSE SMKTFLKRAE EEIIRVQAQE SVALSLVKEI TEYFHGNSAK 300
  301 EEAHPFRIFL VVRDFLGVVD RVCKEVGMIN ERTMVSSAHK FPVPVNPMMP QPLPGLVGRR 360
  361 QSSSSSSSSS TSSSDEDEHN SISLVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 1v9dA
Description: Crystal structure of the core FH2 domain of mouse mDia1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle