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View Structure Prediction Details

Protein: DPYD_ARATH
Organism: Arabidopsis thaliana
Length: 426 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPYD_ARATH.

Description E-value Query
Range
Subject
Range
gi|6177796 - gi|6177796|dbj|BAA86060.1| senescencs-related protein [Pyrus pyrifolia]
274.0 [0..1] [426..1]

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Predicted Domain #1
Region A:
Residues: [1-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASMSFALNR FSGLSSKTTL SADFDPSSRR SFLPPTRVGL KISSAAESEP DLSVTVNGLK  60
   61 MPNPFVIGSG PPGTNYTVMK RAFDEGWGAV IAKTVSLDAS KVINVTPRYA RLRTGSNGSA 120
  121 KTDVIGWQNI ELISDRPLET MLKEFERLKK EYPDRILIAS VMEEYNKTAW EELIDRVEQT 180
  181 GVDALEINFS CPHGMPERRM GAAVGQDCAL LDEVCGWINA KATVPVWAKM TPNITDITEP 240
  241 ARVSLKSGCE GIAAINTIMS VMGIDMKTLR PEPCVEGYST PGGYSYKAVR PIALAKVMNI 300
  301 AKMMKSEFSE DRSLSGIGGV ETGYDAAEFI LLGSNTVQVC TGVMMHGYGH VKTLCAELKD 360
  361 FMKQHNFSTI EEFRGHSLQY FTTHTDLVKR QKEAVEQRKA EKRGLKSDKD WTGDGFVKET 420
  421 ESMVSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.0
Match: 1gt8A
Description: Dihydropyrimidine dehydrogenase, N-terminal domain; Dihydropyrimidine dehydrogenase, domain 4; Dihydropyrimidine dehydrogenase, domain 3; Dihydropyrimidine dehydrogenase, domain 2; Dihydropyrimidine dehydrogenase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dihydroorotate dehydrogenase activity 2.73800716363956 bayes_pls_golite062009
dihydroorotate oxidase activity 2.35584458985229 bayes_pls_golite062009
catalytic activity 1.94749091175302 bayes_pls_golite062009
dihydropyrimidine dehydrogenase (NADP+) activity 1.76080169529176 bayes_pls_golite062009
oxidoreductase activity 1.34004057547793 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 0.708198550325532 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle