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View Structure Prediction Details

Protein: MLH1_ARATH
Organism: Arabidopsis thaliana
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MLH1_ARATH.

Description E-value Query
Range
Subject
Range
MUTL_PSEPK - DNA mismatch repair protein MutL OS=Pseudomonas putida (strain KT2440) GN=mutL PE=3 SV=1
473.0 [0..27] [689..5]

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Predicted Domain #1
Region A:
Residues: [1-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDDSSLTAE MEEEESPATT IVPREPPKIQ RLEESVVNRI AAGEVIQRPV SAVKELVENS  60
   61 LDADSSSISV VVKDGGLKLI QVSDDGHGIR REDLPILCER HTTSKLTKFE DLFSLSSMGF 120
  121 RGEALASMTY VAHVTVTTIT KGQIHGYRVS YRDGVMEHEP KACAAVKGTQ IMVENLFYNM 180
  181 IARRKTLQNS ADDYGKIVDL LSRMAIHYNN VSFSCRKHGA VKADVHSVVS PSRLDSIRSV 240
  241 YGVSVAKNLM KVEVSSCDSS GCTFDMEGFI SNSNYVAKKT ILVLFINDRL VECSALKRAI 300
  301 EIVYAATLPK ASKPFVYMSI NLPREHVDIN IHPTKKEVSL LNQEIIIEMI QSEVEVKLRN 360
  361 ANDTRTFQEQ KVEYIQSTLT SQKSDSPVSQ KPSGQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.69897
Match: 1bknA
Description: DNA mismatch repair protein MutL
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [396-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTQKVPVNKM VRTDSSDPAG RLHAFLQPKP QSLPDKVSSL SVVRSSVRQR RNPKETADLS  60
   61 SVQELIAGVD SCCHPGMLET VRNCTYVGMA DDVFALVQYN THLYLANVVN LSKELMYQQT 120
  121 LRRFAHFNAI QLSDPAPLSE LILLALKEED LDPGNDTKDD LKERIAEMNT ELLKEKAEML 180
  181 EEYFSVHIDS SANLSRLPVI LDQYTPDMDR VPEFLLCLGN DVEWEDEKSC FQGVSAAIGN 240
  241 FYAMHPPLLP NPSGDGIQFY SKRGESSQEK SDLEGNVDME DNLDQDLLSD AENAWAQREW 300
  301 SIQHVLFPSM RLFLKPPASM ASNGTFVKVA SLEKLYKIFE RC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1bgwA
Description: TOPOISOMERASE RESIDUES 410-1202,
Matching Structure (courtesy of the PDB):

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