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View Structure Prediction Details

Protein: NFXL1_ARATH
Organism: Arabidopsis thaliana
Length: 1188 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFXL1_ARATH.

Description E-value Query
Range
Subject
Range
gi|115764748, gi... - gi|115966263|ref|XP_001197817.1| PREDICTED: similar to receptor protein Notch1 [Strongylocentrotus p...
343.0 [0..63] [921..341]
NOTC1_XENLA - Neurogenic locus notch homolog protein 1 OS=Xenopus laevis GN=notch1 PE=1 SV=3
343.0 [0..67] [923..263]
gi|114627589 - gi|114627589|ref|XP_520371.2| PREDICTED: notch1 isoform 2 [Pan troglodytes]
341.0 [0..67] [923..264]
gi|109467917 - gi|109467917|ref|XP_342393.3| PREDICTED: similar to Neurogenic locus notch homolog protein 1 precurs...
336.0 [0..67] [923..281]
gi|31339069 - gi|31339069|dbj|BAC77038.1| transmembrane receptor Notch1 B [Mus musculus]
336.0 [0..67] [923..249]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQVRRDRS DDRSHRFNHQ QTWIPRNSST SSVVVNEPLL PPNTDRNSET LDAGSASRPV  60
   61 YLQRQHNASG PPSYNHHQRS SNIGPPPPNQ HRRYNAPDNQ HQRSDNIGPP QPNQHRRYNA 120
  121 PDNQHQRSDN SGPPQPYRHR RNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [144-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APENQHQRSD NIGPPPPNRQ RRNNASGTLP DNRQRVASRT RPVNQGKRVA KEENVVLTDP  60
   61 NLPQLVQELQ EKLVKSSIEC MICYDKVGRS ANIWSCSSCY SIFHINCIKR WARAPTSVDL 120
  121 LAEKNQGDNW RCPGCQSVQL TSSKEISYRC F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [295-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGKRRDPPSD PYLTPHSCGE PCGKPLEKEF APAETTEEDL CPHVCVLQCH PGPCPPCKAF  60
   61 APPRSCPCGK KMVTTRCSER RSDLVCGQRC DKLLSCGRHQ CERTCHVGPC DPCQVLVNAT 120
  121 CFCKKKVETV ICGDMNVKGE LKAEDGVYSC SFNCGKPLGC GNHFCSEVCH PGPCGDCDLL 180
  181 PSRVKTCYCG NTRLEEQIRQ SCLDPIPSCS NVCRKLLPCR LHTCNEMCHA GDCPPCLVQV 240
  241 NQKCRCGSTS RAVECYITTS SEAEKFVCAK PCGRKKNCGR HRCSERCCPL LNGKKNDLSG 300
  301 DWDPHVCQIP CQKKLRCGQH SCESLCHSGH CPPCLEMIFT DLTCACGRTS IPPPLSCGTP 360
  361 VPSCQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [660-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPCPIPQPCG HSDTHGCHFG DCPPCSTPVE KKCVGGHVVL RNIPCGLKDI RCTKICGKTR  60
   61 RCGMHACART CHPEPCDSFN ESEAGMRVTC RQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [753-1005]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGAPRTDCRH TCAALCHPSA PCPDLRCEFS VTITCSCGRI TATVPCDAGG RSANGSNVYC  60
   61 AAYDEASVLQ KLPAPLQPVE SSGNRIPLGQ RKLSCDDECA KLERKRVLQD AFDITPPNLE 120
  121 ALHFSENSAM TEIISDLYRR DPKWVLAVEE RCKFLVLGKA RGSTSALKVH IFCPMQKDKR 180
  181 DTVRLIAERW KLGVSNAGWE PKRFTVVHVT AKSKPPTRII GARGGAISIG GPHPPFYDSL 240
  241 VDMDPGLVVS FLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 2dtgE
Description: No description for 2dtgE was found.

Predicted Domain #6
Region A:
Residues: [1006-1188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPREANISAL VLRFGGECEL VWLNDKNALA VFHDHARAAT AMRRLEHGSV YHGAVVVQSG  60
   61 GQSPSLNNVW GKLPGSSAWD VDKGNPWRRA VIQESDDSWG AEDSPIGGSS TDAQASALRS 120
  121 AKSNSPIVTS VNRWSVLEPK KASTSTLEPI AQIEESSSSK TTGKQPVEGS GEEVVDDWEK 180
  181 VCE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle