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View Structure Prediction Details

Protein: UPL5_ARATH
Organism: Arabidopsis thaliana
Length: 873 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for UPL5_ARATH.

Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLSRSSADD STNNANRSYS AVAGTDNKRK RDEDSSDYVG VAESLEMLKK QEIDADHMAA  60
   61 SAQQTLISWR SGENSRSLSS SGECSSSNRP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.09691
Match: 2ojrA
Description: No description for 2ojrA was found.

Predicted Domain #2
Region A:
Residues: [91-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTRLQIFVR MMSGGKTIVI HAEKYDTVEK LHQRIEWKTK IPALEQRVIY KGKQLQRENS  60
   61 LTYYSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.09691
Match: 1yj1A
Description: X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [157-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQDASLQLVA RMQSTEHPVA WQTIDDIMYT ISRMYKGENL QSNINEKIVT FFAMIPVESD  60
   61 ESIAKYLNIF SNSSVPAALV MLY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [240-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSLERNKSC AKSSVKLFLS NCVALPKNQK NYCLPIVLEF CKLLRKVCPD QKLYVTCRNT  60
   61 LGSMLETFDN PHGVYNDQYE TFGVEIFPFF TELTGLLLNE LAQNSGPSFC DFQKVSSFWQ 120
  121 QLRKVIELKV AFPIPIVLPM QSTALEAEIR HLHRLFGSLL TTMDLCMCRV ESSLADKEVG 180
  181 NSETMSSSWS QYLSILKIIN SMSNIYQGAK GQLAVMLNKN KVSFSALVVK FAKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [474-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDDHQWIFEY KEATNFEARR HLAMLLFPDV KEDFEEMHEM LIDRSNLLSE SFEYIVGASP  60
   61 EALHGGLFME FKNEEATGPG VLREWFYLVC QEIFNPKNTL FLRSADDFRR FSPNPASKVD 120
  121 PLHPDFFEFT GRVIALALMH KVQVGVLFDR VFFLQLAGLK ISLEDIKDTD RIMYNSCKQI 180
  181 LEMDPEFFDS NAGLGLTFVL ETEELGKRDT IELCPDGKLK AVNSKNRKQY VDLLIERRFA 240
  241 TPILEQVKQF SRGFTDMLSH SVPPRSFFKR LYLEDLDGML RGGENPISID DWKAHTEYNG 300
  301 FKETDRQIDW FWKILKKMTE EEQRSILFFW TSNKFVPVEG FRGLSSKLYI YRLYEANDRL 360
  361 PLSHTCFYRL CIPRYPTITL MEQRLRLIAQ DHVSSSFGKW 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 116.0
Match: 1zvdA
Description: Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle