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View Structure Prediction Details

Protein: HEM4_ARATH
Organism: Arabidopsis thaliana
Length: 321 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEM4_ARATH.

Description E-value Query
Range
Subject
Range
gi|71489436, gi|... - gi|71544542|ref|ZP_00665566.1| Uroporphyrin-III C-methyltransferase, C-terminal [Syntrophobacter fum...
287.0 [0..2] [321..193]

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Predicted Domain #1
Region A:
Residues: [1-62]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLLLSHCS ILSFQPPLSS SSSFHSSHIQ SLSKPVFASP SPIRNSISSS VSSSSSSVSS  60
   61 SN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1pjqA
Description: Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [63-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIPQVVVTRE RGKNNQIIKA LEKNGISSLE LPLIQHARGP DFDRLASVLN DKSFDWIIIT  60
   61 SPEAGSVFLE AWKTASSPEV QIGVVGAGTA RVFEEAMKSA DGLLHVAFTP SKATGKVLAS 120
  121 ELPEKVGKRS SVLYPASLKA GNDIVEGLSK RGFEVVRLNT YTTVPVQSVD TVLLQQALSA 180
  181 PVLSVASPSA VRAWLHLIQN EEQWSNYVAC IGETTASAAR RLGLKNVYYP EKPGLEGWVE 240
  241 SIMEALGAHA DSSNPSSRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.09691
Match: 1jr2A
Description: Uroporphyrinogen III synthase (U3S, HemD)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle