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View Structure Prediction Details

Protein: SMC6B_ARATH
Organism: Arabidopsis thaliana
Length: 1057 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for SMC6B_ARATH.

Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKSGARASD SFIKQRSGSG SILRIKVENF MCHSNLQIEF GEWVNFITGQ NGSGKSAILT  60
   61 ALCVAFGCRA RGTQRAATLK DFIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1us8A
Description: The Rad50 signature motif: essential to ATP binding and biological function
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [85-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGCSYAVVQV EMKNSGEDAF KPEIYGGVII IERRITESAT ATVLKDYLGK KVSNKRDELR  60
   61 ELVEHFNIDV ENPCVVMSQD KSREFLHSGN DKDKFKFFFK ATLLQQVNDL LQSIYEHLTK 120
  121 ATAIVDELEN TIKPIEKEIS ELRGKIKNME QVEEIAQRLQ QLKKKLAWSW VYDVDRQLQE 180
  181 QTEKIVKLKE RIPTCQAKID WELGKVESLR DTLTKKKAQV ACLMDESTAM KREIESFHQS 240
  241 AKTAVREKIA LQEEFNHKCN YVQKIKDRVR RLERQVGDIN EQTMKNTQAE QSEIEEKLKY 300
  301 LEQEVEKVET LRSRLKEEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [404-619]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCFLEKAFEG RKKMEHIEDM IKNHQKRQRF ITSNINDLKK HQTNKVTAFG GDRVINLLQA  60
   61 IERNHRRFRK PPIGPIGSHV TLVNGNKWAS SVEQALGTLL NAFIVTDHKD SLTLRGCANE 120
  121 ANYRNLKIII YDFSRPRLNI PRHMVPQTEH PTIFSVIDSD NPTVLNVLVD QSGVERQVLA 180
  181 ENYEEGKAVA FGKRLSNLKE VYTLDGYKMF FRGPVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [620-913]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTLPPLSRRP SRLCASFDDQ IKDLEIEASK EQNEINQCMR RKREAEENLE ELELKVRQLK  60
   61 KHRSQAEKVL TTKELEMHDL KNTVAAEIEA LPSSSVNELQ REIMKDLEEI DEKEAFLEKL 120
  121 QNCLKEAELK ANKLTALFEN MRESAKGEID AFEEAENELK KIEKDLQSAE AEKIHYENIM 180
  181 KNKVLPDIKN AEANYEELKN KRKESDQKAS EICPESEIES LGPWDGSTPE QLSAQITRMN 240
  241 QRLHRENQQF SESIDDLRMM YESLERKIAK KRKSYQDHRE KLMACKNALD SRWA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [914-1057]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFQRNASLLR RQLTWQFNAH LGKKGISGHI KVSYENKTLS IEVKMPQDAT SNVVRDTKGL  60
   61 SGGERSFSTL CFALALHEMT EAPFRAMDEF DVFMDAVSRK ISLDALVDFA IGEGSQWMFI 120
  121 TPHDISMVKS HERIKKQQMA APRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1xewY
Description: Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle