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View Structure Prediction Details

Protein: CGS1_ARATH
Organism: Arabidopsis thaliana
Length: 563 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CGS1_ARATH.

Description E-value Query
Range
Subject
Range
gi|1742961 - gi|1742961|emb|CAA64383.1| cystathionine gamma-synthase [Arabidopsis thaliana]
531.0 [0..1] [563..1]
gi|8439541 - gi|8439541|gb|AAF74981.1|AF082891_1 cystathionine gamma-synthase isoform 1 [Solanum tuberosum]
498.0 [0..1] [563..1]
gi|40806079 - gi|40806079|gb|AAR92031.1| cystathionine gamma synthase [Lycopersicon esculentum]
498.0 [0..1] [563..1]
gi|92870065 - gi|92870065|gb|ABE79443.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzymes [Medicago trunca...
482.0 [0..1] [563..1]
gi|113204691 - gi|113204691|gb|ABI34092.1| cystathionine gamma-synthase [Medicago sativa]
476.0 [0..1] [563..1]
gi|3202028, gi|7... - pir||T12288 O-succinylhomoserine (thiol)-lyase (EC 4.2.99.9) - common ice plant, gi|3202028|gb|AAC1...
472.0 [0..2] [563..3]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVSSFQCPT IFSSSSISGF QCRSDPDLVG SPVGGSSRRR VHASAGISSS FTGDAGLSSR  60
   61 ILRFPPNFVR QLSIKARRNC SNIGVAQIVA AKWSNNP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSALPSAAAA AATSSASAVS SAASAAAASS AAAAPVAAAP PVVLKSVDEE VVVAEEGIRE  60
   61 KIGSVQLTDS KHSFLSSDGS LTVHAGERLG RGIVTDAITT PVVNTSAYFF KKTAELIDFK 120
  121 EKRSVSFEYG RYGNPTTVVL EDKISALEGA ESTLVMASGM CASTVMLLAL VPAGGHIVTT 180
  181 TDCYRKTRIF MENFLPKLGI TVTVIDPADI AGLEAAVNEF KVSLFFTESP TNPFLRCVDI 240
  241 ELVSKICHKR GTLVCIDGTF ATPLNQKALA LGADLVVHSA TKYIGGHNDV LAGCICGSLK 300
  301 LVSEIRNLHH VLGGTLNPNA AYLIIRGMKT LHLRVQQQNS TAFRMAEILE AHPKVSHVYY 360
  361 PGLPSHPEHE LAKRQMTGFG GVVSFEIDGD IETTIKFVDS LKIPYIAPSF GGCESIVDQP 420
  421 AIMSYWDLPQ EERLKYGIKD NLVRFSFGVE DFEDVKADIL QALEAI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.0
Match: 1i41A
Description: Cystathionine gamma-synthase, CGS
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle