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View Structure Prediction Details

Protein: HIS8_ARATH
Organism: Arabidopsis thaliana
Length: 466 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS8_ARATH.

Description E-value Query
Range
Subject
Range
gi|3982577 - gi|3982577|gb|AAC83459.1| histidinol dehydrogenase [Thlaspi goesingense]
657.0 [0..3] [466..1]

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Predicted Domain #1
Region A:
Residues: [1-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLSRLSL LSSPRISIST HAPRKGYVCC SMKSYRLSEL SSSQVDSLKS RPRIDFSSIF  60
   61 ATVNPIIDAV RSNGDNAVKE YTERFDKVQL NKVVEDMSEL SVPELDSNVK EAFDVAYDNI 120
  121 YAFHLAQKST EKSVENMKGV RCKRVSRSIG SVGLYVPGGT AVLPSTALML AIPAQIAGCK 180
  181 TVVLATPPSK DGSICKEVLY CAKRAGVTHI LKAGGAQAIA AMAWGTDSCP KVEKIFGPGN 240
  241 QYVTAAKMIL QNSEAMVSID MPAGPSEVLV IADEHASPVY IAADLLSQAE HGPDSQVVLV 300
  301 VVGDSVDLNA IEEEIAKQCK SLPRGEFASK ALSHSFTVFA RDMIEAISFS NLYAPEHLII 360
  361 NVKDAEKWEG LIENAGSVFI GPWTPESVGD YASGTNHVLP TYGYARMYSG VSLDSFLKFM 420
  421 TVQSLTEEGL RNLGPYVATM AEIEGLDAHK RAVTLRLKDI EAKQLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 172.0
Match: 1k75A
Description: L-histidinol dehydrogenase HisD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.80804701752928 bayes_pls_golite062009
histidinol dehydrogenase activity 2.32012109012499 bayes_pls_golite062009
oxidoreductase activity 2.31275077585879 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.24875477727877 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2.22720948878196 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle