YRC Public Data Repository - Protein Structure Prediction

Protein:	FTSH1_ARATH
Organism:	Arabidopsis thaliana
Length:	716 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSH1_ARATH.

Description	E-value	Query Range	Subject Range
gi\|205357195, gi... - gi\|205357195\|ref\|ZP_02345811.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|197248059, gi... - gi\|197248059\|ref\|YP_002148220.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|195873641, gi... - gi\|195873641\|ref\|ZP_02697399.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194471603, gi... - gi\|194471603\|ref\|ZP_03077587.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|194447870, gi... - gi\|194447870\|ref\|YP_002047324.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|194442507, gi... - gi\|194442507\|ref\|YP_002042552.1\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ent... gi\|205348591, gi... - gi\|205360607\|ref\|ZP_02684667.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205343557, gi... - gi\|205359745\|ref\|ZP_02831638.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|205359196, gi... - gi\|205359196\|ref\|ZP_02668061.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente... gi\|62181804, gi\|... - gi\|62181804\|ref\|YP_218221.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|205333758, gi... - gi\|205358490\|ref\|ZP_02656962.2\| ATP-dependent metallopeptidase HflB [Salmonella enterica subsp. ente...	596.0	[0..98]	[715..1]
FTSH_SALTI - Cell division protease ftsH OS=Salmonella typhi GN=hflB PE=3 SV=1 FTSH_SALTY - Cell division protease ftsH OS=Salmonella typhimurium GN=hflB PE=3 SV=1 gi\|214000933 - gi\|214000933\|ref\|ZP_03411668.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|224585091, gi... - gi\|224585091\|ref\|YP_002638890.1\| cell division protein [Salmonella enterica subsp. enterica serovar ... gi\|56129482, gi\|... - gi\|56415225\|ref\|YP_152300.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|238910089 - gi\|238910089\|ref\|ZP_04653926.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|207858544, gi... - gi\|207858544\|ref\|YP_002245195.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... gi\|213052988 - gi\|213052988\|ref\|ZP_03345866.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... lcl\|NC_016856.1_... - [gene=hflB] [protein=ATP-dependent metalloprotease] [protein_id=YP_005239474.1] [location=complement... gi\|213425426 - gi\|213425426\|ref\|ZP_03358176.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|213852786 - gi\|213852786\|ref\|ZP_03382318.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica s... gi\|29143547, gi\|... - gi\|29143547\|ref\|NP_806889.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|160867488, gi... - gi\|161506141\|ref\|YP_001573253.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. arizonae ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium GN=ftsH PE=3 SV=1 gi\|16762058 - gi\|16762058\|ref\|NP_457675.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica sero... gi\|161616303, gi... - gi\|161616303\|ref\|YP_001590268.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTI - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhi GN=ftsH PE=3 SV=1 gi\|197364155, gi... - gi\|197364155\|ref\|YP_002143792.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ... FTSH_SALTY - ATP-dependent zinc metalloprotease FtsH OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... gi\|205273978, gi... - gi\|205354197\|ref\|YP_002227998.1\| ATP-dependent metalloprotease [Salmonella enterica subsp. enterica ...	595.0	[0..105]	[715..3]
gi\|746401 - gi\|746401\|gb\|AAA97508.1\| ATP-binding protein gi\|188487047, gi... - gi\|188491848\|ref\|ZP_02999118.1\| ATP-dependent metallopeptidase HflB [Escherichia coli 53638], gi\|188... gi\|157068341, gi... - gi\|157162661\|ref\|YP_001459979.1\| ATP-dependent metalloprotease [Escherichia coli HS], gi\|157068341\|g... gi\|157080734, gi... - gi\|157158704\|ref\|YP_001464653.1\| ATP-dependent metalloprotease [Escherichia coli E24377A], gi\|157080... gi\|226839967, gi... - gi\|254038343\|ref\|ZP_04872401.1\| ATP-dependent metalloprotease [Escherichia sp. 1_1_43], gi\|226839967... gi\|253771988, gi... - gi\|253771988\|ref\|YP_003034819.1\| ATP-dependent metalloprotease FtsH [Escherichia coli BL21(DE3)], gi... gi\|237706070, gi... - gi\|237706070\|ref\|ZP_04536551.1\| ATP-dependent metalloprotease [Escherichia sp. 3_2_53FAA], gi\|226899... gi\|194411725, gi... - gi\|194430224\|ref\|ZP_03062722.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B171], gi\|1944... tr\|A0A0G3HSQ2\|A0... - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli (strain K12) GN=ftsH PE=3 SV=1 gi\|191168060, gi... - gi\|191168060\|ref\|ZP_03029860.1\| ATP-dependent metallopeptidase HflB [Escherichia coli B7A], gi\|19090...	595.0	[0..98]	[715..1]
gi\|218555748, gi... - gi\|218555748\|ref\|YP_002388661.1\| ATP-dependent metalloprotease [Escherichia coli IAI1], gi\|218362516... gi\|218358002, gi... - gi\|218550461\|ref\|YP_002384252.1\| ATP-dependent metalloprotease [Escherichia fergusonii ATCC 35469], ... gi\|218429032, gi... - gi\|218691468\|ref\|YP_002399680.1\| ATP-dependent metalloprotease [Escherichia coli ED1a], gi\|218429032... gi\|218367017, gi... - gi\|218560248\|ref\|YP_002393161.1\| ATP-dependent metalloprotease [Escherichia coli S88], gi\|218367017\|... gi\|218701947, gi... - gi\|218701947\|ref\|YP_002409576.1\| ATP-dependent metalloprotease [Escherichia coli IAI39], gi\|21837193... gi\|218696883, gi... - gi\|218696883\|ref\|YP_002404550.1\| ATP-dependent metalloprotease [Escherichia coli 55989], gi\|21835361... gi\|218706798, gi... - gi\|218706798\|ref\|YP_002414317.1\| ATP-dependent metalloprotease [Escherichia coli UMN026], gi\|2184338... FTSH_ECOLI - Cell division protease ftsH (EC 3.4.24.-) - Escherichia coli EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... FTSH_SHIFL - ATP-dependent zinc metalloprotease FtsH OS=Shigella flexneri GN=ftsH PE=3 SV=1 gi\|24053649, gi\|... - gi\|24114467\|ref\|NP_708977.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 301], gi\|24053... gi\|30042775, gi\|... - gi\|30064516\|ref\|NP_838687.1\| ATP-dependent metalloprotease [Shigella flexneri 2a str. 2457T], gi\|300... EG11506 - protease, ATP-dependent zinc-metallo / ATP-dependent membrane protease, complexed with HflCK; regula... gi\|227887899, gi... - gi\|227887899\|ref\|ZP_04005704.1\| M41 family endopeptidase FtsH [Escherichia coli 83972], gi\|227835295... gi\|238863291, gi... - gi\|238902280\|ref\|YP_002928076.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BW2952], gi\|... gi\|251786448, gi... - gi\|251786448\|ref\|YP_003000752.1\| hypothetical protein B21_02994 [Escherichia coli BL21], gi\|24237872... gi\|253975021, gi... - gi\|254163120\|ref\|YP_003046228.1\| protease, ATP-dependent zinc-metallo [Escherichia coli B str. REL60... gi\|253979177, gi... - gi\|254289870\|ref\|YP_003055618.1\| protease, ATP-dependent zinc-metallo [Escherichia coli BL21(DE3)], ... gi\|169890548, gi... - gi\|170082713\|ref\|YP_001732033.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|169753500, gi... - gi\|170018572\|ref\|YP_001723526.1\| ATP-dependent metalloprotease [Escherichia coli ATCC 8739], gi\|1697... gi\|215266566, gi... - gi\|215488494\|ref\|YP_002330925.1\| ATP-dependent metalloprotease [Escherichia coli O127:H6 str. E2348/... gi\|209920653, gi... - gi\|209920653\|ref\|YP_002294737.1\| ATP-dependent metalloprotease [Escherichia coli SE11], gi\|209913912... gi\|75197127 - gi\|75197127\|ref\|ZP_00707197.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli HS] gi\|75208502 - gi\|75208502\|ref\|ZP_00708822.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B171] gi\|75187984 - gi\|75187984\|ref\|ZP_00701251.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli E24377A] gi\|146028, gi\|89... - gi\|89109941\|ref\|AP_003721.1\| protease, ATP-dependent zinc-metallo [Escherichia coli str. K-12 substr... gi\|91074173, gi\|... - gi\|91212599\|ref\|YP_542585.1\| ATP-dependent metalloprotease [Escherichia coli UTI89], gi\|91074173\|gb\|... gi\|117625472, gi... - gi\|117625472\|ref\|YP_858795.1\| ATP-dependent metalloprotease [Escherichia coli APEC O1], gi\|115514596... gi\|110345010, gi... - gi\|110643418\|ref\|YP_671148.1\| ATP-dependent metalloprotease [Escherichia coli 536], gi\|110345010\|gb\|... gi\|75228765 - gi\|75228765\|ref\|ZP_00715374.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli B7A] gi\|110616592, gi... - gi\|110807044\|ref\|YP_690564.1\| ATP-dependent metalloprotease [Shigella flexneri 5 str. 8401], gi\|1106... gi\|74313715, gi\|... - gi\|74313715\|ref\|YP_312134.1\| ATP-dependent metalloprotease [Shigella sonnei Ss046], gi\|73857192\|gb\|A...	594.0	[0..105]	[715..3]
gi\|75240799 - gi\|75240799\|ref\|ZP_00724697.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli F11]	594.0	[0..105]	[715..3]
FTSH_ECO57 - ATP-dependent zinc metalloprotease FtsH OS=Escherichia coli O157:H7 GN=ftsH PE=3 SV=1 gi\|13363530, gi\|... - gi\|15833311\|ref\|NP_312084.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. Sakai], gi... gi\|254594527, gi... - gi\|254795127\|ref\|YP_003079964.1\| subunit of integral membrane ATP-dependent zinc metallopeptidase [E... gi\|209758260, gi... - pir\|\|D85981 cell division protein HflB/FtsH proteinase [imported] - Escherichia coli (strain O157:H7... gi\|209160879, gi... - gi\|209399479\|ref\|YP_002272648.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. ... gi\|195938397 - gi\|195938397\|ref\|ZP_03083779.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 str. EC4024] gi\|15803718, gi\|... - gi\|15803718\|ref\|NP_289752.1\| ATP-dependent metalloprotease [Escherichia coli O157:H7 EDL933], gi\|125... gi\|217319989, gi... - gi\|217327622\|ref\|ZP_03443705.1\| ATP-dependent metallopeptidase HflB [Escherichia coli O157:H7 str. T...	594.0	[0..105]	[715..3]
gi\|82778492, gi\|... - gi\|82778492\|ref\|YP_404841.1\| ATP-dependent metalloprotease [Shigella dysenteriae Sd197], gi\|81242640...	594.0	[0..105]	[715..3]
gi\|81246995, gi\|... - gi\|82545584\|ref\|YP_409531.1\| ATP-dependent metalloprotease [Shigella boydii Sb227], gi\|81246995\|gb\|A...	594.0	[0..105]	[715..3]
gi\|37528354, gi\|... - gi\|37528354\|ref\|NP_931699.1\| ATP-dependent metalloprotease [Photorhabdus luminescens subsp. laumondi...	593.0	[0..98]	[715..1]
gi\|75260106 - gi\|75260106\|ref\|ZP_00731384.1\| COG0465: ATP-dependent Zn proteases [Escherichia coli E22]	591.0	[0..109]	[715..2]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASNSLLRSS SNFFLGSHII ISSPTPKTTR KPSFPFSFVS RAKYQITRSS QDENSPNGKP  60
   61 NSPFSSQVAL AAILLSSISS SPLALAVVDE PASPSVVIES QAVKPSTPSP LFIQNEILKA 120
  121 PSPKSSDLPE G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [132-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQWRYSEFLN AVKKGKVERV RFSKDGSVVQ LTAVDNRRAS VIVPNDPDLI DILAMNGVDI  60
   61 SVSEGESSGN DLFTVIGNLI FPLLAFGGLF LLFRRAQGGP GGGPGGLGGP MDFGRS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	23.180456
Match:	PF06480.6
Description:	No description for PF06480.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [248-716]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSKFQEVPET GVSFADVAGA DQAKLELQEV VDFLKNPDKY TALGAKIPKG CLLVGPPGTG  60
   61 KTLLARAVAG EAGVPFFSCA ASEFVELFVG VGASRVRDLF EKAKSKAPCI VFIDEIDAVG 120
  121 RQRGAGMGGG NDEREQTINQ LLTEMDGFSG NSGVIVLAAT NRPDVLDSAL LRPGRFDRQV 180
  181 TVDRPDVAGR VKILQVHSRG KALGKDVDFD KVARRTPGFT GADLQNLMNE AAILAARREL 240
  241 KEISKDEISD ALERIIAGPE KKNAVVSEEK KRLVAYHEAG HALVGALMPE YDPVAKISII 300
  301 PRGQAGGLTF FAPSEERLES GLYSRSYLEN QMAVALGGRV AEEVIFGDEN VTTGASNDFM 360
  361 QVSRVARQMI ERFGFSKKIG QVAVGGPGGN PFMGQQMSSQ KDYSMATADI VDAEVRELVE 420
  421 KAYKRATEII TTHIDILHKL AQLLIEKETV DGEEFMSLFI DGQAELYIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	125.0
Match:	2ce7A
Description:	EDTA treated
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits