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View Structure Prediction Details

Protein: AGO1_ARATH
Organism: Arabidopsis thaliana
Length: 1048 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for AGO1_ARATH.

Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRKRRTDAP SEGGEGSGSR EAGPVSGGGR GSQRGGFQQG GGQHQGGRGY TPQPQQGGRG  60
   61 GRGYGQPPQQ QQQYGGPQEY QGRGRGGPPH QGGRGGYGGG RGGGPSSGPP QRQSVPELHQ 120
  121 ATSPTYQAVS SQPTLSEVSP TQVPEPTVLA QQFEQLSVEQ GAPSQAIQPI PSSSKAFKFP 180
  181 MRPGKGQSGK RCIVKANHFF AEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [204-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDKDLHHYDV TITPEVTSRG VNRAVMKQLV DNYRDSHLGS RLPAYDGRKS LYTAGPLPFN  60
   61 SKEFRINLLD EEVGAGGQRR EREFKVVIKL VARADLHHLG MFLEGKQSDA PQEALQVLDI 120
  121 VLRELPTSRY IPVGRSFYSP DIG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [347-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKQSLGDGLE SWRGFYQSIR PTQMGLSLNI DMSSTAFIEA NPVIQFVCDL LNRDISSRPL  60
   61 SDADRVKIKK ALRGVKVEVT HRGNMRRKYR ISGLTAVATR ELTFPVDERN TQKSVVEYFH 120
  121 ETYGFRIQHT QLPCLQVGNS NRPNYLPMEV CKIVEGQRYS KRLNERQITA LLKVTCQRPI 180
  181 DREKDILQTV QLNDYAKDNY AQEFGIKIST SLASVEARIL PPPWLKYHES GREG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1r4kA
Description: Solution Structure of the Drosophila Argonaute 1 PAZ Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [581-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TCLPQVGQWN MMNKKMINGG TVNNWICINF SRQVQDNLAR TFCQELAQMC YVSGMAFNPE  60
   61 PVLPPVSARP EQVEKVLKTR YHDATSKLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [670-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGKEIDLLIV ILPDNNGSLY GDLKRICETE LGIVSQCCLT KHVFKMSKQY MANVALKINV  60
   61 KVGGRNTVLV DALSRRIPLV SDRPTIIFGA DVTHPHPGED SSPSIAAVVA SQDWPEITKY 120
  121 AGLVCAQAHR QELIQDLFKE WKDPQKGVVT GGMIKELLIA FRRSTGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1w9hA
Description: The Structure of a Piwi protein from Archaeoglobus fulgidus.
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [837-1048]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPLRIIFYRD GVSEGQFYQV LLYELDAIRK ACASLEAGYQ PPVTFVVVQK RHHTRLFAQN  60
   61 HNDRHSVDRS GNILPGTVVD SKICHPTEFD FYLCSHAGIQ GTSRPAHYHV LWDENNFTAD 120
  121 GLQSLTNNLC YTYARCTRSV SIVPPAYYAH LAAFRARFYM EPETSDSGSM ASGSMARGGG 180
  181 MAGRSTRGPN VNAAVRPLPA LKENVKRVMF YC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 3dlbA
Description: No description for 3dlbA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle