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View Structure Prediction Details

Protein: unc-75
Organism: Caenorhabditis elegans
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-75.

Description E-value Query
Range
Subject
Range
gi|73981466 - gi|73981466|ref|XP_850830.1| PREDICTED: similar to trinucleotide repeat containing 4 isoform 2 [Cani...
305.0 [0..23] [514..1]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQQHEMRA SSTSSTDSNG FPVKDPDAIK LFVGQIPRNL EEKDLRHLFE QFGKIYEFTI  60
   61 LKDKYTGMHK GCAFLTYCHR DSAVRCQATL HDQKTLPGMN RAMQVKPADT DSRPASPKDK 120
  121 MDDKKLFIGM LSKQQSEDEV RALFATFGEL DEVTVLRGAD GASKGCAFVK YKHGLDAHMA 180
  181 ISALHGSQTM PGASSSLVVK YADTEKERQN RRMQQMAAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.221849
Match: 2dhsA
Description: No description for 2dhsA was found.

Predicted Domain #2
Region A:
Residues: [220-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMLNPMLVN QVGMQYNAYQ QVLQQQSLAA QTNAMASAAY LPLLQQQTTD PLHVLQLQAA  60
   61 AAAAQAAANP VLSQQTQQQQ QQQQQLAAQL QLQSAAAQNP HYALAAQALA QQQAAQQAQA 120
  121 VVAHSHAQVH QHQTAQVTST ASHAQTENPA ASSYGSLAAA AAAANYSSLL SGMESQHNAA 180
  181 AALQLAQIQQ QAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [413-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AALPMVTPRE VLGPDGCNLF IYHLPQEFGD AELIQMFAPF GHIVSAKVFV DRATNQSKCF  60
   61 GFVSYDNIHS SQAAITAMNG FQIGMKRLKV QLKRPRNESR PY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 2cpzA
Description: solution structure of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1
Matching Structure (courtesy of the PDB):

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