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View Structure Prediction Details

Protein: sphk-1
Organism: Caenorhabditis elegans
Length: 423 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sphk-1.

Description E-value Query
Range
Subject
Range
sphk-1 - Diacylglycerol kinase catalytic domain (presumed) status:Partially_confirmed UniProt:Q18425 protein_...
251.0 [0..1] [423..51]

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Predicted Domain #1
Region A:
Residues: [1-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGTICCCCR SDAEENEQLT SVILSRKPPP QEQCRGNLLV FINPNSGTGK SLETFANTVG  60
   61 PKLDKSLIRY EVVVTTGPNH ARNVLMTKAD LGKFNGVLIL SGDGLVFEAL NGILCREDAF 120
  121 RIFPTLPIGI VPSGSGNGLL CSVLSKYGTK MNEKSVMERA LEIATSPTAK AESVALYSVK 180
  181 TDNQSYASFL SIGWGLMADI DIDSEKWRKS LGHHRFTVMG FIRSCNLRSY KGRLTYRPYK 240
  241 PKGFHPSSNV FSVYEKTTQQ RIDDSKVKTN GSVSDSEEET METKFQNWTL PDSDETLAVG 300
  301 SSDLEETVVI EDNFVNIYAV TLSHIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 2bonA
Description: No description for 2bonA was found.

Predicted functions:

Term Confidence Notes
kinase activity 2.76633393386992 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.49560915337842 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.43985991144271 bayes_pls_golite062009
transferase activity 1.63159199531284 bayes_pls_golite062009
catalytic activity 0.33446102778142 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [327-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADGPFAPSAK LEDNRIHLSY ILWKDIGTRV NIAKYLLAIE HETHLDLPFV KHVEVSSMKL  60
   61 EVISEGSHVV LDGEVVDTKT IEVASTKNHI SVFSSTA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.31
Match: 2bonA
Description: No description for 2bonA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle