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View Structure Prediction Details

Protein: nhr-88
Organism: Caenorhabditis elegans
Length: 593 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-88.

Description E-value Query
Range
Subject
Range
gi|10198089 - gi|10198089|gb|AAG15179.1| nuclear receptor NHR-88 [Caenorhabditis elegans]
403.0 [0..1] [593..6]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFAPSTVYTY GHHGSGTDED DGQQVMPGMD NGDGQCMVCG DRSAGKHYGV MACYGCKGFF  60
   61 RRTIRSQQTY TCRFTQKCAI DKDQRNACRY CRFQRCLTVG MEPEAIRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [109-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRDVIGKQKN PRKKKMKSDT NSGSIDASLP SPNGCDSPVS NNEDVILSFL LDVEDQATCG  60
   61 NNHITMPIGI SMMMKNDPDF DVSTLFHSQY VRNQESFPIT YAVGRTASVE QLIAALRRYV 120
  121 LSAVHWIDAL FNLAHLTEIH DKTTLLKSVI GPFTIFNIAA RTAQISDGDL ICLCNKSTIN 180
  181 RQPARHLLDT NLVGNNFVGR VIDDLVFPTK KLALTNPEIT ILSALIILDP DARGLSQETS 240
  241 QALLGIRDRV QNALFNLIRD NSNNMTSVTS RFGNLLLLFP PLAKLSSLIG ENVQLAKMFG 300
  301 IPIDSLLVEL YVDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1z5xE
Description: hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [423-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSPELISQGS HARERSDVST QTASLEGASA SMTPDVTSSE FVKMEQNESP SSSEEPMCIG  60
   61 APATSSANAV ATNLAADLLG LLPNFDATGL DLASAAAAAA TSVNYSHFYG FGNLGGSLDD 120
  121 SSSSGTGSVG SFAPHSAPPI SNNVNPFAVH GFFDNSAPNT GVVHNQPFRF V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle