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View Structure Prediction Details

Protein: crn-3
Organism: Caenorhabditis elegans
Length: 594 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for crn-3.

Description E-value Query
Range
Subject
Range
gi|37678370, gi|... - gi|37678370|ref|NP_932979.1| DNA polymerase I [Vibrio vulnificus YJ016], gi|37197109|dbj|BAC92950.1|...
465.0 [0..7] [594..88]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGEESMPDE EQKQSEEEEE MIRKRTLAMR KKVEEIMRNG AGLVRESNGL PKAGADYELY  60
   61 NSYPTFNTFM KRSEQRLNAL MNKVTKSIGC AMRVPDVGSS VEHYTECVIE AQDNIAERAA 120
  121 TLHEALKKAE LDEIVKVPEF ITKAAPTNRK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.09691
Match: 1ut5A
Description: Divalent metal ions (manganese) bound to T5 5'-exonuclease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.845290320008287 bayes_pls_golite062009
hydrolase activity 0.31554871338907 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.12799711467808 bayes_pls_golite062009
nuclease activity 0.0878151841480506 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [151-594]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEAEVSAAMR TFSANIGTVL AEKFRERREE AAQMVVLEKP QKTYNISSDN SQAPFSSKLT  60
   61 VKHHAIEKRT GIVLHDDDES GRRDWISAET ETEEEHPYIA EILHFKVPEA QLKSAECLKF 120
  121 TALKDTPLTM IDTKEKLEAL TKTLNSVKEF AVDLEHHQMR SYLGLTCLIQ ISTRDEDFII 180
  181 DPFPIWDHVG MLNEPFANPR ILKVFHGSDS DVLWLQRDYG VHVVNLFDTY VKVKKLLNEL 240
  241 DKFVTPFECY QMMMITKEKQ EEEERKEAER KKLEEGDLPK TMFSHHDAPI NRKPEFDAKL 300
  301 LNVDTLKLVP DDPNKPKDPE PSPMEESSSE PQIFDPSRFT DDQLLSKKAM KRKRDAARRN 360
  361 IDVSVVLGES SSSSDPKKKK SDDDAPVEDF DYEKADSSAF EKPVRDNNAD FDPFHQKYRL 420
  421 KNKTKKNMAM KKSSNRQGTI NYKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.221849
Match: 2hbjA
Description: No description for 2hbjA was found.

Predicted functions:

Term Confidence Notes
catalytic activity 0.722279828632226 bayes_pls_golite062009
hydrolase activity 0.29272620969648 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.24934115119652 bayes_pls_golite062009
nuclease activity 0.239989310123501 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle