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View Structure Prediction Details

Protein: nhr-49
Organism: Caenorhabditis elegans
Length: 486 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-49.

Description E-value Query
Range
Subject
Range
gi|5702091 - gi|5702091|gb|AAD47137.1|AF061181_1 green fluorescent protein-estrogen receptor alpha fusion [Mammal...
321.0 [0..2] [454..438]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNLQMIVIM DLVDPLAEPC AVCGDKSTGT HYGVISCNGC KGFFRRTVLR DQKFTCRFNK  60
   61 RCVIDKNFRC ACRYCRFQKC VQVGMKREAI QFERDPVGSP TSGASLNGTP FKKDRSPGYE 120
  121 NGNSNGVGSN GMGQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMRTVPQSSS VIDALMEMEA RVNQEMCNRY RRSQIFANGS GGSNGNDTDI QQGSDSGASA  60
   61 FAPPNRPCTT EVDLNEISRT TLLLMVEWAK TINPFMDLSM EDKIILLKNY APQHLILMPA 120
  121 FRSPDTTRVC LFNNTYMTRD NNTDLNGFAA FKTSNITPRV LDEIVWPMRQ LQMREQEFVC 180
  181 LKALAFLHPE AKGLSNSSQI MIRDARNRVL KALYAFILDQ MPDDAPTRYG NILLLAPALK 240
  241 ALTQLLIENM TLTKFFGLAE VDSLLSEFIL DDINDHSTAP VSLQQHLSSP TTLPTNGVSP 300
  301 LNPAGSVGSV SSVSGITPTG MLSATLAAPL AIHPLQSQDS ILNSEQNNHM L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1z5xU
Description: hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle