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View Structure Prediction Details

Protein: kcnl-2
Organism: Caenorhabditis elegans
Length: 635 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kcnl-2.

Description E-value Query
Range
Subject
Range
kcnl-2 - status:Partially_confirmed UniProt:Q6BET2 protein_id:CAH10785.1
365.0 [0..1] [635..1]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASPMLQHM YSLDESSLMG VSHHSPYRQQ RKRRAGISGA ATGGSHQRDG PFACAGGNGY  60
   61 SSAGFSNGRG FPPLGGRSPQ SSFDSNQDV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQISMNWMRM NGLGPSLRPF LNSGNHTPKK TVIHNSQSTN HISRIGSLRR MHAADASIDG  60
   61 KLSLSGTQGD VAAACGETAS RKSVSIAYSN DLEAGGKGNG AIGDDSTVPL MDEKDDNSGG 120
  121 RLIRREILHE KRRHVSDRAL AFAIMGIILM IIENELRTAY VIRPGSSLSH LLKFFIIFTT 180
  181 TALLSFVGYF HVIEIQLFMN ANAADDWMVA LSFRRTCQIG LELLICMLCP LPIEFIAPFM 240
  241 NDRFHDKTLY AVNVFLSIMM FFRLYWLCRV MLLHSRVFTD ASSRSIAGLN RVNFNARFIL 300
  301 KTLMTICPGT MLMIFTAFLW IIAGWILRLC EREYMTPDKY NDINYVNSIW LVAITFLSVG 360
  361 YGDIVPKTNC GRSMAIVTGI LGTCASSMVV AVIARKLELT RAEKHVHNFM QDTQLTKQLK 420
  421 HSAANVLRET WFIFKFRKLV EKPDFGKIRK HQRKFLLAIY EMRRVRRDQR KLAENL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [566-635]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSLGDVAKTS SNTYELVHDV HSTQEGLSLR ITAIEHQLSD ISRELSSLAE LLRGSVIITS  60
   61 DQMSNERKVS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 2q0aA
Description: No description for 2q0aA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle