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View Structure Prediction Details

Protein: egl-4
Organism: Caenorhabditis elegans
Length: 749 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-4.

Description E-value Query
Range
Subject
Range
egl-4 - cyclic-GMP-dependent protein kinase status:Confirmed UniProt:O76360 protein_id:AAD36954.1
566.0 [0..8] [749..40]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYGSSRHHMD SFSSNDGGAF LVQVGTRTFE AHELQKLIPQ LEEAISRKDA QLRQQQTIVE  60
   61 GHIKRISELE GEVTTLQREC DKLRSVLEQK AQSAASPGGQ P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2ezwA
Description: Solution structure of the docking and dimerization domain of the type I alpha regulatory subunit of protein kinase A (RIalpha D/D)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [102-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSPSPRTDQL GNDLQQKAVL PADGVQRAKK IAVSAEPTNF ENKPATLQHY NKTVGAKQMI  60
   61 RDAVQKNDFL KQLAKEQIIE LVNCMYEMRA RAGQWVIQEG EPGDRLFVVA EGELQVSREG 120
  121 ALLGKMRAGT VMGELAILYN CTRTASVQAL TDVQLWVLDR SVFQMITQRL GMERHSQLMN 180
  181 FLTKVSIFQN LSEDRISKMA DVMDQDYYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.30103
Match: 1rgsA
Description: REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [311-687]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGHYIIRQGE KGDAFFVINS GQVKVTQQIE GETEPREIRV LNQGDFFGER ALLGEEVRTA  60
   61 NIIAQAPGVE VLTLDRESFG KLIGDLESLK KDYGDKERLA QVVREPPSPV KIVDDFREEF 120
  121 AQVTLKNVKR LATLGVGGFG RVELVCVNGD KAKTFALKAL KKKHIVDTRQ QEHIFAERNI 180
  181 MMETSTDWIV KLYKTFRDQK FVYMLLEVCL GGELWTTLRD RGHFDDYTAR FYVACVLEGL 240
  241 EYLHRKNIVY RDLKPENCLL ANTGYLKLVD FGFAKKLASG RKTWTFCGTP EYVSPEIILN 300
  301 KGHDQAADYW ALGIYICELM LGRPPFQASD PMKTYTLILK GVDALEIPNR RIGKTATALV 360
  361 KKLCRDNPGE RLGSGSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.09691
Match: 2ozoA
Description: No description for 2ozoA was found.

Predicted Domain #4
Region A:
Residues: [688-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVNDIRKHRW FMGFDWEGLR SRTLKPPILP KVSNPADVTN FDNYPPDNDV PPDEFSGWDE  60
   61 GF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1ctpE
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle