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View Structure Prediction Details

Protein: shc-1
Organism: Caenorhabditis elegans
Length: 316 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for shc-1.

Description E-value Query
Range
Subject
Range
gi|73961017 - gi|73961017|ref|XP_865175.1| PREDICTED: similar to SHC transforming protein 1 (SH2 domain protein C1...
241.0 [0..7] [310..143]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNVEPSFAE ELRSSGVSLS ATYLGSVPVV ESINVMVSEM RVQVVSECIQ HVAATVGVTA  60
   61 AREINPVVSR VIGEVKKENF PVDINIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.522879
Match: 1n3hA
Description: Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [88-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKMIKIIKQS RLIQRHPFSF FSFGAQGQKG TDTELMFGYI AKNKDGTDRR CHVVFIEDVH  60
   61 KLIDVLTTAI NVNTFDAQAN ASTSNDGFTV PAPPMRHRSS LHRQSFVSNC RAPTVTEDVV 120
  121 GKVWYHGNLS REDAQALLKT EGDFLVRQSD HTPGKYVLSG RTAENEHKHL ILLDNHNRVR 180
  181 TRDRTFSNIS ELIDYHVNNG MAVRSEGRDR ETSLNLIRPV PCPGSDDIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.39794
Match: 2h8hA
Description: No description for 2h8hA was found.

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