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View Structure Prediction Details

Protein: aka-1
Organism: Caenorhabditis elegans
Length: 605 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aka-1.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
269.0 [0..1] [551..2232]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEVPDMDDL LDEMESDLVK KCCSVQSKPL LPPTSIGMQP RGIKHNPAPR TVVTVSKFVI  60
   61 SEDMNEQMEG NINIDTSQLP NTFQTKSSFP PNSDERNI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKENEVSARQ EIAHKLKSVH NYSDATNFDP SKKVITQKFS QESEPESEPE PEPEEVSEVE  60
   61 EDTLVPETQI ISNLNATARD TEPTATISKP NLDLDTEMED MLAYLNDESV DKSSLKDKPA 120
  121 REEGGRDSIE ESANESALYQ FADRFSELVI SEALNHRKMH YDPAVKEFYE ANDSVPDVFA 180
  181 MSLDSTHSSL NSFNADNHNY LSEPENSSKK ERMQSVAEEN EASEEPTQSS SETEKNLQNE 240
  241 KIDVEFIENS EAIVQNESED VPESNSTSGT VLENIEDHLE SDVVIENGSE SSFVNEKMNE 300
  301 ASTAHLVAEQ SVVDDSEIHL ETEDQETLSP ETADSSTNKN SDEFPDEGSQ SEASVNNEEV 360
  361 LENVEHVEDE CTVVDAVNEN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [479-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDSSIEENDE ENTENRPRFD SSIATIHVLH ESDSDESATP RRERRLTESE LQLGKTSPYW  60
   61 IPDSECPNCM LCNTRFTIIT RRHHCRACGR VLCGSCCNEK AFLEYLQEEG KKLQAVRLLP 120
  121 PQFLAVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 1jocA
Description: Eea1; Eea1 homodimerisation domain
Matching Structure (courtesy of the PDB):

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