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View Structure Prediction Details

Protein: CE31291
Organism: Caenorhabditis elegans
Length: 642 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE31291.

Description E-value Query
Range
Subject
Range
gi|4753778 - gi|4753778|emb|CAB41971.1| methylenetetrahydrofolate reductase [Homo sapiens]
882.0 [0..23] [642..54]

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Predicted Domain #1
Region A:
Residues: [1-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLSKNGVE TDENAVVEEK ITLESGKSWS PKHYELLHER IERLIDEKQQ FFSLEFFPPR  60
   61 FVNGVPNFLE RVERLSEGGS VFVDMTWHMG SDPANVDKVT SSSSIAASML DYCGVDTMLH 120
  121 MTCVQYNKAD TLKHLEQAKA MGLRSILALR GDLPPGTELE DTHQFRALDM IRWIREEYGN 180
  181 YFSIGCAGYP LGHPQAPSYK ADLMYLKAKC DAGANFVITQ LFFEAETFEK FVRDCREIGI 240
  241 TQPIIPGIMP IMGYESIKRI AKLSQLEIPQ HILDDLEPIK HDDDAVQKYG TERCIEMCRR 300
  301 LLDNGTAPSI HLYTMNREGS IREILKSLGL WKLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.39794
Match: 1zp3A
Description: E. coli Methylenetetrahydrofolate Reductase (oxidized)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [335-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDRVFPWKNR SQHPIRCLES VRPIYWSFRP RSYITRTRDW DQFPNGRWGN SSSPAFGDVS  60
   61 SYYLSNLTTV RNADDRLAMF GANIESFEDV KRVFINYITQ APNADGVKVT VLPWTEAETG 120
  121 VQPETSLISE QLVWCNENGI LTVNSQPSVN GAPSTDPLVG WGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [498-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGGYCYQKAY LECFMTAELS DKLIQIIERE FPVRVNYHAI NKDSTFDKTN SEETTPIAVT  60
   61 WGVFPGSEIA QPTVVDPLSF RAWRDEAYQM WMAQWGDFYP KESKSYGVIK AVHDEFRLVT 120
  121 LVDNDFQKPS VLFDVLQKAL DELKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle