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View Structure Prediction Details

Protein: daf-16
Organism: Caenorhabditis elegans
Length: 508 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-16.

Description E-value Query
Range
Subject
Range
daf-16 - status:Confirmed UniProt:O16850 protein_id:AAK82919.1
232.0 [0..1] [508..1]
gi|157747851 - gi|157747851|ref|XP_001669020.1| Hypothetical protein CBG12825 [Caenorhabditis briggsae AF16]
gi|187029402, gi... - gi|39595858|emb|CAE67361.1| Hypothetical protein CBG12825 [Caenorhabditis briggsae], gi|187029402|em...
193.0 [0..1] [508..1]
gi|94372318 - gi|94372318|ref|XP_982945.1| PREDICTED: similar to forkhead box O6 [Mus musculus]
167.0 [0..36] [507..8]
gi|50757941 - gi|50757941|ref|XP_425369.1| PREDICTED: similar to forkhead box K2 isoform 1; interleukin enhancer b...
141.0 [0..44] [483..697]
gi|68382628 - gi|68382628|ref|XP_690445.1| PREDICTED: similar to forkhead box O6 [Danio rerio]
133.0 [0..127] [507..13]
gi|74007728 - gi|74007728|ref|XP_549066.2| PREDICTED: similar to Putative fork head domain transcription factor AF...
131.0 [0..24] [507..2]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEMLVDQGT DASSSASTST SSVSRFGADT FMNTPDDVMM NDDMEPIPRD RCNTWPMRRP  60
   61 QLEPPLNSSP IIHEQIPEED ADLYGSNEQC GQLGGASSNG ST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMLHTPDGSN SHQTSFPSEM SESPDDTVSG KKTTTRRNAW GNMSYAELIT TAIMASPEKR  60
   61 LTLAQVYEWM VQNVPYFRDK GDSNSSAGWK NSIRHNLSLH SRFMRIQNEG AGKSSWWVIN 120
  121 PDAKPGRNPR RTRERSNTIE TTTKAQLEKS RRGAKKRIKE RALMGSLHST LNGNSIAGSI 180
  181 QTISHDLYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1e17A
Description: Afx (Foxo4)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [292-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDSMQGAFDN VPSSFRPRTQ SNLSIPGSSS RVSPAIGSDI YDDLEFPSWV GESVPAIPSD  60
   61 IVDRTDQMRI DATTHIGGVQ IKQESKPIKT EPIAPPPSYH ELNSVRGSCA QNPLLRNPIV 120
  121 PSTNFKPMPL PGAYGNYQNG GITPINWLST SNSSPLPGIQ SCGIVAAQHT VASSSALPID 180
  181 LENLTLPDQP LMDTMDVDAL IRHELSQAGG QHIHFDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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