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View Structure Prediction Details

Protein: acr-7
Organism: Caenorhabditis elegans
Length: 538 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-7.

Description E-value Query
Range
Subject
Range
gi|118781880, gi... - gi|118781880|ref|XP_311918.3| AGAP002974-PA [Anopheles gambiae str. PEST], gi|116129303|gb|EAA08125....
gi|51873075 - gi|51873075|gb|AAU12503.1| nicotinic acetylcholine receptor subunit alpha 1 [Anopheles gambiae]
430.0 [0..6] [537..1]

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Predicted Domain #1
Region A:
Residues: [1-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMVQSIQIVL PVALFFLIVF NGFTVEGSKK EAQLYRDLLT NYSYLVRPVR NPKKALTVTM  60
   61 KVFIQQVLLV DAKHQMIEVN AWLKYIWTDF RLRWNPLDYE NITSVRFQGE DQIWQPDILL 120
  121 YNRYIEDEQE SFDITYKTNA VAYSDGVINW IPPGIFKLSC KMDITLFPFD EQICFMKFGS 180
  181 WTYHGFALDL RLDVVKGQEP SADLSTYITN GEWHLLSAPA RREEKFYKCC KEPYPTVKFY 240
  241 LHLRRRTFYY VFNVVLPTLL VSFMSLLAFC LPATDLSEKI GLQTTILLSV CFFLTILSEM 300
  301 TPTTSEAVPL LGVFFSALTF IVAMSTTFTI LVLNIRYRQI TNHYL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.045757
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [346-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPMFRSIFLE CLPWLMMMKR PDHKFRRGSS YRDSSADQCV QCAKNAELKS ILRGTDNQQQ  60
   61 IETNTFYPFP TETLSLNRKV GDGLFIQRRC QIHEEARSEK FTHGMLACEK SLRENGSELA 120
  121 NILVTILKMY EVMVSQVERI RKRIALKRKR KDIQDEWKFA AQAVDRFCLI IFTIVFIICC 180
  181 FIFVAIPPIK ILD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.0
Match: 1oedE
Description: Acetylcholine receptor protein, gamma chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle