YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: apl-1
Organism: Caenorhabditis elegans
Length: 684 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apl-1.

Description E-value Query
Range
Subject
Range
gi|82542243 - gi|82542243|gb|ABB82033.1| amyloid precursor protein variant 1 [Sus scrofa]
407.0 [0..6] [681..1]

Back

Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVGKLMIGL LIPILVATVY AEGSPAGSKR HEKFIPMVAF SCGYRNQYMT EEGSWKTDDE  60
   61 RYATCFSGKL DILKYCRKAY PSMNITNIVE YSHEVSISDW CREEGSPCKW THSVRPYHCI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1mwpA
Description: N-terminal domain of the amyloid precursor protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGEFHSEALQ VPHDCQFSHV NSRDQCNDYQ HWKDEAGKQC KTKKSKGNKD MIVRSFAVLE  60
   61 PCALDMFTGV EFVCCPNDQT NKTD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1owtA
Description: Amyloid beta a4 protein copper binding domain (domain 2)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [205-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQKTKEDEDD DDDEDDAYED DYSEESDEKD EEEPSSQDPY FKIANWTNEH DDFKKAEMRM  60
   61 DEKHRKKVDK VMKEWGDLET RYNEQKAKDP KGAEKFKSQM NARFQKTVSS LEEEHKRMRK 120
  121 EIEAVHEERV QAMLNEKKRD ATHDYRQALA T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1rw6A
Description: human APP core domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [356-684]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVNKPNKHSV LQSLKAYIRA EEKDRMHTLN RYRHLLKADS KEAAAYKPTV IHRLRYIDLR  60
   61 INGTLAMLRD FPDLEKYVRP IAVTYWKDYR DEVSPDISVE DSELTPIIHD DEFSKNAKLD 120
  121 VKAPTTTAKP VKETDNAKVL PTEASDSEEE ADEYYEDEDD EQVKKTPDMK KKVKVVDIKP 180
  181 KEVTIEEEKK APKLVETSVQ TDDEDDDEDS SSSTSSESDE DEDKNIKELR VDIEPIIDEP 240
  241 ASFYRHDKLI QSPEVERSAS SVFQPYVLAS AMFITAICII AFAITNARRR RAMRGFIEVD 300
  301 VYTPEERHVA GMQVNGYENP TYSFFDSKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.045757
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle