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View Structure Prediction Details

Protein: plk-1
Organism: Caenorhabditis elegans
Length: 648 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for plk-1.

Description E-value Query
Range
Subject
Range
plk-1 - status:Confirmed UniProt:P34331 protein_id:AAM22025.1
503.0 [0..1] [648..1]

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Predicted Domain #1
Region A:
Residues: [1-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRLPNIAKP PQKSNQRKEK APPEVPALIA DKDRGTYYEK GRFLGKGGFA HCYELTNRAT  60
   61 REVVAGKVVP KSMLVKQYQR DKMTQEVQIH RELGHINIVK LFNFFEDNLN VYITLELCAR 120
  121 RSLMELHKRR KAVTEPEARY FTHQIVDGVL YLHDLNIIHR DMKLGNLFLN DDLVVKIGDF 180
  181 GLATTVNGDE RKKTLCGTPN YIAPEVLNKA GHSFEVDIWA VGCILYILLF GQPPFESKSL 240
  241 EETYSRIRHN NYTIPSIATQ PAASLIRKML DPEPTRRPTA KQVQRDGFFK SGFMPTRLPV 300
  301 SCLTMVPKFG GHETSMMEEN VAPRGVDARS QRPLNGRAGL SALPQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 2ou7A
Description: No description for 2ou7A was found.

Predicted Domain #2
Region A:
Residues: [347-648]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVSNNADRER AQQQAAEATF REPEDAYLSQ LFHQVAVLLE QRIPGLEEEE AALDGYQSPE  60
   61 CLPVFWISKW VDYSDKYGIG YQLCDNSVGV LFNDNSRIML DQAGNELTYI EKSNKEHYFS 120
  121 MHSGEMPGLL NKKVTLLKYF RSYMNDHLVK AGEGSEQRAG DDLARLPTLR VWFRTKSAIV 180
  181 LHLSNGTVQI NFFNDHVKMM MCPLMQAVTF IDQNKRMLTY KLNNLQRNGC PEKFLHRLKY 240
  241 AKTMIERLMS DANVVSQNPA RQPDMPRSMA AARSASAGSR GPNQAASHLP QSASGSNIHP 300
  301 RR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 1q4kB
Description: The polo-box domain of Plk1 in complex with a phospho-peptide
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle