YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: avr-15
Organism: Caenorhabditis elegans
Length: 657 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for avr-15.

Description E-value Query
Range
Subject
Range
gi|2285910, gi|3... - ref|NP_506350.2| altered AVeRmectin sensitivity AVR-15, ivermectin-sensitive glutamate-gated chlorid...
460.0 [0..1] [657..1]

Back

Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGRLRRGFI LFPQLFLLFV SISSIFLFVL VECKPPKSLN RMRSKGTYNA AAFNSPSMIN  60
   61 NGLLLAGFEN NDTSRETRES YEEYKDDIDH LLEGDLTFYD EGADTAAGDV VITSETPVEK 120
  121 HKEVHFKNEP EEEEIGKEDD GGGEAEEGEY EEENGSDAEE EEESPEKVEP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [171-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSTITTEAQ TTTTPEEVTQ DVSDNIEDDE DARPKSEEHS PKHAASSSDL FEDDDQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [227-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTLESIARL SAPAHVPIEQ PQTSDTEILE HLLTRGYDHR VRPPGEDGTI HGGPVVVSVN  60
   61 MLLRSISKID NVNMEYSVQL TFRESWVDKR LSFGVKGDAQ PDFLILTAGQ EIWMPDSFFQ 120
  121 NEKQAYKHMI DKPNVLIRVH KDGTILYSVR ISLVLSCPMH LQYYPMDVQQ CFIDLASYAY 180
  181 TTKDIEYVWK EETPVQLKAG LSSSLPSFQL TNTSTTYCTS KTNTGSYSCL RTIIQLRRQF 240
  241 SYYLLQLYIP SCMLVIVSWV SFWIDRTAVP ARVTLGVTTL LTMTTQSSGI NAKLPPVAYI 300
  301 KAIDVWIGAC MTFIFCALLE FAWVTYIANK QDANKRARTE REK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.09691
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [570-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AELPFLQNSH NDVWVPREVA EQEREVMTVR MNRRQTNSVW KWIKTKTEWN DKSKRADLIS  60
   61 RVMFPVLFLT FNISYWTHYG QYGVAIST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1oedA
Description: Acetylcholine receptor protein, alpha chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle