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View Structure Prediction Details

Protein: lgc-26
Organism: Caenorhabditis elegans
Length: 486 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-26.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
350.0 [0..17] [486..95]

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Predicted Domain #1
Region A:
Residues: [1-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLRLISIG VLINFHFGNA ASQSTDERKL EAQLLKGYNS KVRPVKVEST VTQVAVYLNI  60
   61 AHVEKVDEHE QTALVHGHLM ASWTDEYLKW ERKATNISTL SIASSKLWQP ALQLYNSARG 120
  121 NSWSLYLTGL PAIVYNTGKV WSRGTFSFFV TCQFDFTNWP YDQQSCPIVI TDWVYGLGQV 180
  181 NLSDPATAAG YGKPTIRLSY DPIDETNKRH VGGWEVIDSW KKHCYWGPKG CLDAEPDGNP 240
  241 DWYWSLLEFG ITLKRHLPYF SLTIVMPMVS TSLMILLGFW IENFDFNVFL ITLNIALQAT 300
  301 YGSNILSRMP PGSGRTPKIV HLYSIGLLIS AFQVVLIVMS NFLRVRLPSH YEFDFGYDIT 360
  361 EIPKKFGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.69897
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [369-486]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRFFTTKGLS FDPQELLNPA QLTSEAEIQK EASTSIGISN PLAESGSDTD LLINLPKNSE  60
   61 ADLSERSETL GMPDSEKTQK ESQKKMRKLE IQLLHIKRFA FFFVIFVYLF AILLVLAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.30103
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle