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View Structure Prediction Details

Protein: bre-1
Organism: Caenorhabditis elegans
Length: 368 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bre-1.

Description E-value Query
Range
Subject
Range
gi|56459650, gi|... - gi|56459650|ref|YP_154931.1| dTDP-D-glucose 4,6-dehydratase [Idiomarina loihiensis L2TR], gi|5617866...
320.0 [0..20] [364..1]

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Predicted Domain #1
Region A:
Residues: [1-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHEVSTTPA AELAAFRARK VALITGISGQ DGSYLAELLL SKGYKVHGII RRSSSFNTAR  60
   61 IEHLYSNPIT HHGDSSFSLH YGDMTDSSCL IKLISTIEPT EVYHLAAQSH VKVSFDLPEY 120
  121 TAEVDAVGTL RLLDAIHACR LTEKVRFYQA STSELYGKVQ EIPQSEKTPF YPRSPYAVAK 180
  181 MYGYWIVVNY REAYNMFACN GILFNHESPR RGETFVTRKI TRSVAKISLG QQESIELGNL 240
  241 SALRDWGHAR EYVEAMWRIL QHDSPDDFVI ATGKQFSVRE FCNLAFAEIG EVLQWEGEGV 300
  301 EEVGKNKDGV IRVKVSPKYY RPTEVETLLG NAEKAKKTLG WEAKVTVPEL VKEMVASDII 360
  361 LMKSNPMA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.69897
Match: 1t2aA
Description: Crystal structure of human GDP-D-mannose 4,6-dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle