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View Structure Prediction Details

Protein: CE18868
Organism: Caenorhabditis elegans
Length: 643 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18868.

Description E-value Query
Range
Subject
Range
gi|63101113, gi|... - gi|66472344|ref|NP_001018536.1| drebrin-like [Danio rerio], gi|63101113|gb|AAH95818.1| Zgc:112450 [D...
266.0 [0..1] [361..1]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLNYHAHGK EIEASYRRAS DDSDGDKWVI FDYEGNSNTL RVKEEGTGGL EEFADSFSSG  60
   61 KLQFGVISVR LSSDVFPKIV LVHWQGEGVP TLRLASTTPH AEEFRRFLKT VHIVLHARSE 120
  121 IDIEPDAIRK EVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.0
Match: 1x67A
Description: Solution structure of the cofilin homology domain of HIP-55 (drebrin-like protein)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [134-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPAANANAI VESTYSMPEK VNSVYQPTNA HSELSSEARE NFWSTTNQEE KRRQADEKVA  60
   61 HAKQQKQYEA DRDRTAAAIH TKAEDFQPEK VNSVYKPTKP HVELKTVKRE EFWSKMNEEE 120
  121 KLRQEEEKTA REQAHKQFEA DRQRMASEIH SKTENYQPDK VTSVYKPTKP HVEISSSARE 180
  181 EFWSKMNEEE QRRQAEEKEA QAQKQKEFET DRKRIADDLH GKAQISDKPV PSSVNPAPAP 240
  241 AP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.59
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #3
Region A:
Residues: [376-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSAGLVGSR KELFSSKPSG PVLPKPQVNG SPKKWPPVGT TSPPREPVNR LTEPDEPSTY  60
   61 TPKPIAYEPE PMVYKPEAMK PAVSYDAYEE PPAEPAPPTF LAPTPVIAPP PPEPTPAPSH 120
  121 YASQYDAPPV HESFEPAVPP VSAPSHYASQ YDAPPEPIDS HSSSSQLPAH IASQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [550-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDMPPVMPEE PVFAPKSSPI KVAAPPIDQY DFPPAVAEQN AMALWDYQAA DDTEISFDPD  60
   61 DIITDIDQVD SGWWKGRAPS GRVGLFPANY VKLI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1x69A
Description: Solution structures of the SH3 domain of human Src substrate cortactin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle