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View Structure Prediction Details

Protein: CE16858
Organism: Caenorhabditis elegans
Length: 561 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE16858.

Description E-value Query
Range
Subject
Range
CE25225 - status:Partially_confirmed UniProt:Q9N566 protein_id:AAF59425.1
736.0 [0..109] [559..29]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTEGTSTHF IVSSSSRSDH QGHKQGLLWE AGAISAIFLV VDHQEPESHR AAYPWCFAPL  60
   61 DLRN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [65-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIFWVPVSFL QIIDGLMFQL PDPSDETFSK CSEFKLIRTG VAELFLSIAC DRRSSHSPLS  60
   61 RIEELEVHQP NETFVNNGTY TSLEDLVNIS NLTQWCIEME VLSLGYYNYI ADGLNSSEKF 120
  121 KEVMKRLDGL NSTNVNIFYN ALHANVEILN QMNIPFSVEN QFLHNISETL KIRIIAELES 180
  181 SSISDKAKTH IKKSIETSKQ FFAFYDHNDV KVFETAKLTY ETEYYRLKSL LSPEDIQRKV 240
  241 SEPILRIGAT TASMENLMSK IRRFDVNFLF HAIIASPEND AFQYNGGNHL LTVITRNDLT 300
  301 QQEKTMADTY FITTHEIMHL IYPVANSYIN ESVWTGALEC TLRDVKMLGE TDAVKPVDGW 360
  361 YKPEIGYEDL INVMAMRVLM KMAAEKSVNE QQLKEALETV IGGLCKHTGR KNELIPDHHP 420
  421 LEISRNAAVR QYPLFNSLYG CKAGDRMFAK PNEYCKPLGD PINVEDFLIK NETRKDVGGF 480
  481 LKDVLNTAER FNFTYEL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.968
Match: 1dmtA
Description: Neutral endopeptidase (neprilysin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.313713481761242 bayes_pls_golite062009
hydrolase activity 0.0940978605930549 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle