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View Structure Prediction Details

Protein: nhr-49
Organism: Caenorhabditis elegans
Length: 477 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-49.

Description E-value Query
Range
Subject
Range
nhr-49 - Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confir...
303.0 [0..1] [477..10]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVDPLAEP CAVCGDKSTG THYGVISCNG CKGFFRRTVL RDQKFTCRFN KRCVIDKNFR  60
   61 CACRYCRFQK CVQVGMKREA IQFERDPVGS PTSGASLNGT PFKKDRSPGY ENGNSNGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.154902
Match: 2a66A
Description: Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [119-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNGMGQENM RTVPQSSSVI DALMEMEARV NQEMCNRYRR SQIFANGSGG SNGNDTDIQQ  60
   61 GSDSGASAFA PPNRPCTTEV DLNEISRTTL LLMVEWAKTI NPFMDLSMED KIILLKNYAP 120
  121 QHLILMPAFR SPDTTRVCLF NNTYMTRDNN TDLNGFAAFK TSNITPRVLD EIVWPMRQLQ 180
  181 MREQEFVCLK ALAFLHPEAK GLSNSSQIMI RDARNRVLKA LYAFILDQMP DDAPTRYGNI 240
  241 LLLAPALKAL TQLLIENMTL TKFFGLAEVD SLLSEFILDD INDHSTAPVS LQQHLSSPTT 300
  301 LPTNGVSPLN PAGSVGSVSS VSGITPTGML SATLAAPLAI HPLQSQDSIL NSEQNNHML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.0
Match: 2gl8A
Description: No description for 2gl8A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle