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View Structure Prediction Details

Protein: egl-3
Organism: Caenorhabditis elegans
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-3.

Description E-value Query
Range
Subject
Range
egl-3 - prohormone convertase 2 status:Confirmed UniProt:Q10575 protein_id:CAB01635.1
397.0 [0..4] [556..111]

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Predicted Domain #1
Region A:
Residues: [1-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNTHVDLIC VFLSIFIGIG EAVDVYTNHF HVHLKEGGGL EDAHRIAKRH GFINRGQVAA  60
   61 SDNEYHFVQP ALVHARTRRS AGHHAKLHND DENAEASYDF SSNDPFPYPR YTDDWFNSHG 120
  121 TRCAGEIVAA RDNGVCGVGV AYDGKVAGIR MLDQPYMTDL IEANSMGHEP SKIHIYSASW 180
  181 GPTDDGKTVD GPRNATMRAI VRGVNEGRNG LGSIFVWASG DGGEDDDCNC DGYAASMWTI 240
  241 SINSAINNGE NAHYDESCSS TLASTFSNGG RNPETGVATT DLYGRCTRSH SGTSAAAPEA 300
  301 AGVFALALEA NPSLTWRDLQ HLTVLTSSRN SLFDGRCRDF PSLGINDNHR DSHGNCSHFE 360
  361 WQMNGVGLEY NHLFGFGVLD AAEMVMLAMA WKTSPPRYHC TAGLIDTPHE IPADGNLILE 420
  421 INTDGCAGSQ FEVRYLEHVQ AVVSFNSTRR GDTTLYLISP MGTRTMILSR RPKDDDSKDG 480
  481 FTNWPFMTTH TWGENPTGKW RLVARFQGPG AHAGTLKKFE LMLHGTREAP YNLIEPIVGQ 540
  541 TNKKLDTVQK AHKRSH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1p8jA
Description: Furin, C-terminal domain; Furin, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.06747679108558 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle