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View Structure Prediction Details

Protein: lgc-32
Organism: Caenorhabditis elegans
Length: 497 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-32.

Description E-value Query
Range
Subject
Range
gi|73992736 - gi|73992736|ref|XP_543097.2| PREDICTED: similar to Neuronal acetylcholine receptor protein, alpha-4 ...
314.0 [0..172] [487..93]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHFFLFVHF FKFSIFDAKF KLPMYQLFTV LRKIHWHRAD FFKQNILSHY FIPENNLIYP  60
   61 NFLDLILKMK YRIWILLIFI PIVVLCDDCT SDEDVIADLL GRNSHSSGEI VIKSNYKIAK 120
  121 WLYNSVAHEL ST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [133-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGFFEMSWTH LYSYFQKIFQ YRKFDNSKSS CQKKLLKNWK IFLKIRKMLS LSRNVYIIAT  60
   61 IYVKIYKNLH YKMCKLLFVL VRKICKFIKN RQLDRIMAGT NTTLDFTNLN ACHKTVRIKS 120
  121 LLHIFWLPHV YFPFSYNLEE SRNLYNIEIH ESGNITLSKR LKQSIPCKEQ SDSHPFSNNT 180
  181 CTLSWKYTNL DNYQKIVIEP SNLMDSVERE HSRQFILKDV TFESSGDDEQ RLHYTITQTP 240
  241 QYLLLHFFFP ALLFLIPPWL SLLLGPMAIT RCIILMTSLI LLSNHYDRNV TVFPIDASLN 300
  301 AISIWQLFTY IYVIGIVIEL IIITLFASMG RSKTCCFAKR RSAKYEMEPL YEEMNDLRQR 360
  361 KTRLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.30103
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle