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View Structure Prediction Details

Protein: cdc-14
Organism: Caenorhabditis elegans
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc-14.

Description E-value Query
Range
Subject
Range
gi|55665697, gi|... - gi|55665697|emb|CAH70069.1| CDC14 cell division cycle 14 homolog A (S. cerevisiae) [Homo sapiens], g...
604.0 [0..7] [619..1]

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Predicted Domain #1
Region A:
Residues: [1-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREDHSPRRN NTIENTLTEL LPNRLYFGCF PNPDAIDKSD KSVKKTCFIN INNKFHYEPF  60
   61 YEDFGPWNLS VLYRLCVQVG KLLEVEEKRS RRVVLFCQDD GTGQYDKIRV NTAYVLGAYL 120
  121 IIYQGFSADD AYLKVSSGET VKFVGFRDAS MGSPQYLLHL HDVLRGIEKA LKFGWLDFSD 180
  181 FDYEEYEFYE RVENGDFNWI IPGKILSFCG PHNESREENG YPYHAPDVYF DYFRENKVST 240
  241 IVRLNAKNYD ASKFTKAGFD HVDLFFIDGS TPSDEIMLKF IKVVDNTKGG VAVHCKAGLG 300
  301 RTGTLIACWM MKEYGLTAGE CMGWLRVCRP GSVIGPQQPY LIEKQKFCWS LSQSNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.0
Match: 1ohcA
Description: Proline directed phosphatase CDC14b2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [357-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHLTQNKEEK RNVRRLVNQV DDINLGEERI SPKSRENTRP NILRRRVQVQ NGRSTAPVTI  60
   61 APAGTSESRR STKPSRVVDE 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [437-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TALDDQGRSQ GDRLLQLKAK HQHESETTSP NSSSSRRFVK SSTPQMTVPS QAYLNRNREP  60
   61 IIVTPSKNGT SSGTSSRQLK TTPNGNVAYR TRNSSGNTTS TLTRTPASAV FPSMASRRSE 120
  121 TTRYLSPTTP IKPMSPSYTD GTSPRYKARL RSENPIGSTT STPFSLQPQI TKCSLTAESK 180
  181 PPKRILSMPG TSKSTSSLKK IQVSRPRPYP STGVRVELCA NGKSYDIRPR KEAHVIPGAG 240
  241 LAANTEALLG VCKLVNTLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle