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View Structure Prediction Details

Protein: CE06555
Organism: Caenorhabditis elegans
Length: 365 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06555.

Description E-value Query
Range
Subject
Range
gi|68363004 - gi|68363004|ref|XP_688431.1| PREDICTED: similar to histone H3 methyltransferase DOT1 [Danio rerio]
230.0 [0..39] [361..6]

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Predicted Domain #1
Region A:
Residues: [1-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDANNTEHFY HHRSRNNQQS VLTKNNHVNH LRQIPNLCSL EITMPVIHLS SARKGNAEFK  60
   61 FPNTLHFRQT VKEMFEEIYK PILDAVKVPL PSDAVVGNPD KFSQYIDALN LKLAHPDVLS 120
  121 RVPAKHHEIT STRLCSLTVA IKLAELAYRF SVPDANVLRH YAVGTSTVYG ELHCSQMASF 180
  181 VDQLNMGPSD YFMDLGSGIG HLVNFVAAYA RTQMSVGVEL MDNLAEIAEK NKEFNERLLN 240
  241 HFGKKVYATR FIHGSFTSPA VIREIQTKAT VILANNVRFD PELKLQLKEI LMGCKDRTRI 300
  301 ISSEPLVPSR ARQTNSRRAD DFVKISDESL LNLVDNNVSW TSRKVPFYLT TINRNKVSFF 360
  361 YCVRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.154902
Match: 1nw3A
Description: Catalytic, N-terminal domain of histone methyltransferase Dot1l
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.723277178398499 bayes_pls_golite062009
transferase activity 0.64512166557639 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.54403439349476 bayes_pls_golite062009
methyltransferase activity 0.54389223881989 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle