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View Structure Prediction Details

Protein: twk-8
Organism: Caenorhabditis elegans
Length: 769 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twk-8.

Description E-value Query
Range
Subject
Range
twk-8 - status:Partially_confirmed UniProt:Q7JM20 protein_id:CAE46687.1
383.0 [0..1] [755..1]

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Predicted Domain #1
Region A:
Residues: [1-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVLLRAVGF GRSSNTNRNL RPSSGASGDR LRRPSQMSAG AQSSATRHSQ GDKDKVVQSR  60
   61 IHDQEPEVKE PETWGNRFHR MYKEYHIKYL FPLIFIMFYM LIGAIIFYLL ESGTAEDAAN 120
  121 EEDYKYKRER RLLLLRMEEL VQDTASRRRA YRKKALEEAI DNYEQKLDFA VKNESQWTFM 180
  181 SAMYFAGTLF TTIGYGDIAC ITSAGRIATV IYSCVGIPFM LITLNDLGKF LYNNINGCVK 240
  241 GFEDFTTYLG AFRLCNRRGN GNFQKGDELV TLEAGTTGTT DAPEVSSLAS ELGSERNESD 300
  301 YEDIEDEEER SMPRMSVKVA LGITVGWIFF CSALFKLWED WSYGQSCYFM FISLSTIGLG 360
  361 DVSVQRRDMM VLCFVFVIVG LSLVSMTINV IQVALEDFYV NLIMKLILDY QEKMAAGGDQ 420
  421 MGASVGMMRM WGNNKTAKLL MPLLSKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [448-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKIAMEKVE VKAKNNGIEV PAILTDLDEK SGMPKLFHIE ENTENEEPPK ILEELVQKQI  60
   61 EIEEAAAENA VLFVAHDANT QTDILQQEEK GHQTDEKQYG EEAVQTEAMQ SDNQECETQT 120
  121 EVVHNSIAET QTVIVDYSEA DTMTQPVIVN ESDM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1p7bA
Description: Inward rectifier potassium channel Kirbac1.1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [602-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTDYVQTKEE ELQTYIDKND METLTEIETK NVRIQTPQPV IEQKCIQTED LHEDRKSPSK  60
   61 MSSAKKRLRR AFAGKSKPSR NSVEHPVMSD WKDVEESETA PDEEEEEEIG SVESLHWDPV 120
  121 DGMHAEKQLP VKKLKAMFDS PKGQRKLERK YSSFNKKREN SRSRNKSE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle