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View Structure Prediction Details

Protein: mpk-1
Organism: Caenorhabditis elegans
Length: 376 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mpk-1.

Description E-value Query
Range
Subject
Range
mpk-1 - serine\/threonine kinase (CDC2\/CDC28 subfamily) status:Partially_confirmed UniProt:P39745 protein_i...
380.0 [0..1] [376..69]

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Predicted Domain #1
Region A:
Residues: [1-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGEAVIST VNNVEEVHGQ LFEVAPRYVN LSYIGEGAYG MVASALDTIT RDRVAIKKIS  60
   61 PFEHQTFCQR TLREIKILNR FKHENIINIQ EIIRSETVDS LKDIYIVQCL METDLYKLLK 120
  121 TQKLSNDHVC YFLYQILRGL KYIHSANVLH RDLKPSNLLL NTTCDLKICD FGLARVTDPQ 180
  181 TDHTGFLTEY VATRWYRAPE IMLNSKGYTK SIDVWSVGCI LAEMLSNRPL FPGKHYLDQL 240
  241 NLILAVVGSP SNADLQCIIN DKARSYLISL PHKPKQPWAR LYPGADPRAL DLLDKMLTFN 300
  301 PHNRIDIEQA LAHPYLEQYY DPGDEPVCEE PFTLEMEFDD LPKEKLKELI WEEAEAHHRR 360
  361 MEAEAAARNN GGQNPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.522879
Match: 1wzyA
Description: Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle